Results 51 to 60 of about 7,417 (254)

No Ontological Leaps: A Primer on Scientific Materialism [PDF]

open access: yesIntegral Review, 2011
When the issue is intelligence in nature, arguments about whether science supports neo-Darwinian theory or intelligent design miss the point. The details of evolution or the structure of the brain are irrelevant because biology and neuroscience have ...
Christian de Quincey
doaj  

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Measurement of radon in soils of Lima City - Peru during the period 2016-2017

open access: yesEarth Sciences Research Journal, 2019
Lima City is situated on alluvial fan deposits of rivers flowing through geological formations that contain different levels of uranium. In this paper, a study is made on the average spatial and temporal behavior of radon gas in soils of Lima City. Radon
Luís Vilcapoma Lázaro   +6 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Über die radioaktive Emanation der Bodenluft und der Atmosphäre

open access: yes, 1905
ÜBER DIE RADIOAKTIVE EMANATION DER BODENLUFT UND DER ATMOSPHÄRE Über die radioaktive Emanation der Bodenluft und der Atmosphäre ([1]) Binding ( - ) Title page ([1]) Dedication ([3]) Einleitung.
Brandes, Hermann
core   +1 more source

Symbolic Emanations of God’s Great Title in Monotheism figures in the Islamic Art and Architecture Works [PDF]

open access: yesنگره, 2017
The main issue is to study the quality of semantic implications of God’s great title in Islamic art and architecture works. The purpose is to gain the secret behind immortality of symbolic language of forms, figures, patterns, and structures of Islamic ...
fatemeh akbari
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

SEISMIC ACTIVITY-RELATED ANOMALY DETECTION IN SOIL RADON EMANATION

open access: yes, 2011
Soil Radon Emanation has been continuously monitored along with other geophysical measurements in the seismically active Marmara region of Turkey over the past ten years for understanding the pre-earthquake crustal deformation.
Akgul, Tayfun   +2 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Highly Sensitive Measurements of 222Rn Diffusion and Emanation

open access: yes, 2005
Highly sensitive techniques for determination of the 222Rn emanation from solids and diffusion through different membranes are presented. 222Rn and its daughters are measured via the alpha decays in special proportional counters at the absolute ...
Zuzel, G.
core   +1 more source

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