Results 51 to 60 of about 30,481 (286)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The symbolic epistemological implications of the different mythological set up of the (Egyptian)-Mesopotamian culture compared to the Grecian one [PDF]

, 2017
The Mesopotamian peoples were never really dominated by the reason the way we conceptualize it.
Santarcangelo, Donato
core  

Modeling of electron emission processes accompanying Radon-$\alpha$-decays within electrostatic spectrometers [PDF]

, 2013
Electrostatic spectrometers utilized in high-resolution beta-spectroscopy studies such as in the Karlsruhe Tritium Neutrino (KATRIN) experiment have to operate with a background level of less than 10^(-2) counts per second.
Drexlin, G., Fränkle, F. M., Glück, F., Groh, S., Mertens, S., Wandkowsky, N.   +5 more
core   +4 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Contribution of Emanationist Philosophy to the Development of Environmental Conservation

An-Nida'
The global ecological crisis demonstrates that contemporary ethical frameworks have been insufficient in mitigating the accelerating rate of environmental degradation.
Rifqah Najwa Azizah, Taufik Illahi, Sihabussalam Sihabussalam, Roshiifah Bil Haq   +3 more
doaj   +1 more source

No Ontological Leaps: A Primer on Scientific Materialism [PDF]

Integral Review, 2011
When the issue is intelligence in nature, arguments about whether science supports neo-Darwinian theory or intelligent design miss the point. The details of evolution or the structure of the brain are irrelevant because biology and neuroscience have ...
Christian de Quincey
doaj  

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Radon in the DRIFT-II directional dark matter TPC: emanation, detection and mitigation [PDF]

, 2014
Radon gas emanating from materials is of interest in environmental science and also a major concern in rare event non-accelerator particle physics experiments such as dark matter and double beta decay searches, where it is a major source of background ...
, A. Dorofeev, A. Monte, A. Scarff, A.C. Ezeribe, A.StJ. Murphy, Committee on the Physics of the Universe, D. Loomba, D. Walker, D. Warner, D.P. Snowden-Ifft, E. Daw, E.H. Miller, E.R. Lee, J. Brack, J. Brack ., J. Zeigler, J.-L. Gauvreau, J.A.J. Matthews, J.B.R. Battat, J.L. Harton, J.M. Landers, J.R. Fox, L. Yuriev, L.J. Harmon, M. Gold, M. Pipe, M. Robinson, N. Phan, N.J.C. Spooner, R. Collé, S. Telfer, S.M. Paling, S.W. Sadler   +33 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source