Results 81 to 90 of about 3,015,526 (334)

Equilibrium and Dynamical Evolution of Self-Gravitating System Embedded in a Potential Well

, 2011
Isothermal and self-gravitating systems bound by non-conducting and conducting walls are known to be unstable if the density contrast between the center and the boundary exceeds critical values.
Aarseth, Aarseth, Aarseth, Aarseth, Antonov, Binney, Binney, Chavanis, Chavanis, Chavanis, Chavanis, Cohn, de Vega, de Vega, Dehnen, Eckart, Figer, Hachisu, Heggie, Heggie, Horowitz, Hyung Mok Lee, Ilsang Yoon, Inagaki, Jongsuk Hong, Joshi, Katz, Katz, Katz, King, Lee, Lee, Lynden Bell, Lynden Bell, Mo, Padmanabhan, Padmanabhan, Spitzer, Taruya, Taruya, Taruya, Tsallis, van der Marel, Velazquez   +43 more
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Meta-Learning With Relation Embedding for Few-Shot Deepfake Detection

IEEE Access
The generation of facial images via generative models has gained significant popularity, while the task of discriminating between authentic and synthetic faces has proven to be increasingly challenging. This challenge is exacerbated when novel generative
Xiaoyong Liu, Pengcheng Song, Pei Lu, Yanjun Wang   +3 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Cluster Synchronization for Linearly Coupled Nonidentical Systems With Delays via Aperiodically Intermittent Pinning Control

IEEE Access, 2017
This paper investigates the cluster synchronization problem of linearly coupled complex networks via aperiodically intermittent control (AIC). The dynamical behaviors of nodes in different clusters are assumed to be governed by different dynamical ...
Xiwei Liu, Shaohua Li
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

The extreme vulnerability of interdependent spatially embedded networks

, 2012
Recent studies show that in interdependent networks a very small failure in one network may lead to catastrophic consequences. Above a critical fraction of interdependent nodes, even a single node failure can invoke cascading failures that may abruptly ...
A Bashan, A Bashan, A Bunde, A Vespignani, Amir Bashan, B Nienhuis, CD Brummitt, CM Schneider, CM Schneider, D Li, D Stauffer, I Dobson, J Gao, J Gao, J Hao, M Barthelemy, MPM Den Nijs, R Cohen, R Cohen, R Khanin, R Milo, R Parshani, R Parshani, S Rinaldi, S Son, Sergey V. Buldyrev, Shlomo Havlin, SN Dorogovtsev, SV Buldyrev, SV Buldyrev, U Alon, V Rosato, W Li, X Huang, Y Hu, Yehiel Berezin   +35 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Partition Quantitative Assessment (PQA): A quantitative methodology to\n assess the embedded noise in clustered omics and systems biology data [PDF]

, 2021
Diego A. Camacho-Hernández, Victor E. Nieto-Caballero, José E. León-Burguete, Julio A. Freyre-González   +3 more
openalex   +1 more source