Results 81 to 90 of about 918,238 (314)
Embedding of algebraic systems [PDF]
Berman, Gerald, Silverman, Robert J.
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Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Embedding of weak Markov systems
Let A be a subset of the real line having at least \(n+2\) elements (\(n\geq 0)\), let I be the convex hull of A and let \(Z_ n=\{z_ 0,...,z_ n\}\) be a sequence of linearly independent real valued functions defined on A. If \(\{z_ 0,...,z_ i\}\) is a weak Chebyshev system for \(i=0,...,n\), then \(Z_ n\) is called a weak Markov system.
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RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
The Challenges of Embedded Systems Engineering [PDF]
Embedded system technology has become an important, if not dominating component in the realization of all sorts of high-tech products, machines, and infrastructures. The temptation to create systems with new, powerful, intelligent features has turned embedded software into an essential high-tech ingredient that, exploiting the hardware capabilities ...
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Decrypting cancer's spatial code: from single cells to tissue niches
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Optimization of Wheelchair Control via Multi-Modal Integration: Combining Webcam and EEG
Even though Electric Powered Wheelchairs (EPWs) are a useful tool for meeting the needs of people with disabilities, some disabled people find it difficult to use regular EPWs that are joystick-controlled.
Lassaad Zaway +5 more
doaj +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
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The detection of stages of anaesthesia is mainly performed on evaluating the vital signs of the patient. In addition the frontal one-channel electroencephalogram can be evaluated to increase the correct detection of stages of anaesthesia.
Walther C. +5 more
doaj +1 more source
A unique feature of this open access textbook is to provide a comprehensive introduction to the fundamental knowledge in embedded systems, with applications in cyber-physical systems and the Internet of things. It starts with an introduction to the field and a survey of specification models and languages for embedded and cyber-physical systems.
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