Results 81 to 90 of about 974,557 (269)
Stability-Oriented Deep Learning for Hyperspectral Soil Organic Matter Estimation
SensorsSoil organic matter (SOM) is a key indicator for evaluating soil fertility and ecological functions, and hyperspectral technology provides an effective means for its rapid and non-destructive estimation.
Yun Deng, Yuxi Shi
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
International Journal of Reconfigurable Computing, 2013 This paper describes a novel way to exploit the computation capabilities delivered by modern Field-Programmable Gate Arrays (FPGAs), not only towards a higher performance, but also towards an improved reliability. Computation-specific pieces of circuitry
Xabier Iturbe +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
FedLIC: Personalized Federated Learning With Layer-Wise Importance-Aware Encryption and Compression
IEEE AccessPersonalized federated learning has emerged as a promising paradigm to address statistical heterogeneity across clients in distributed systems. However, existing methods often struggle to jointly balance three key objectives: high predictive accuracy ...
Hengzhou Ye, Fucong Zhao, Yan Chen
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
The Challenges of Embedded Systems Engineering [PDF]
, 2007 Embedded system technology has become an important, if not dominating component in the realization of all sorts of high-tech products, machines, and infrastructures. The temptation to create systems with new, powerful, intelligent features has turned embedded software into an essential high-tech ingredient that, exploiting the hardware capabilities ...
openaire +2 more sources
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source