Results 121 to 130 of about 10,189,459 (300)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Towards A Semiformal Development Methodology for Embedded Systems

open access: yes, 2008
In recent days, the amount of functions has increased significantly in embedded products so that systems development methodologies play an important role to ensure the product’s quality, cost, and time.
Cordeiro, Lucas   +2 more
core   +1 more source

4DO-DETR for otitis media detection

open access: yesScientific Reports
Otitis media (OM) and its complications can cause immense suffering for patients. However, due to the limited number of experts and their knowledge base, human specialists can only handle a limited number of CT images.
Xinyue Zhao   +3 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Fault-tolerant control synthesis and verification of distributed embedded systems

open access: yes, 2014
We deal with synthesis of distributed embedded control systems closed over a faulty or severely constrained communication network. Such overloaded communication networks are common in cost-sensitive domains such as automotive. Design of such systems aims
Soudbakhsh, D.   +14 more
core   +1 more source

Reinforcing Deep Learning-Enabled Surveillance with Smart Sensors

open access: yesSensors
It is critical to solidify surveillance in 3D environments with heterogeneous sensors. This study introduces an innovative deep learning-assisted surveillance reinforcement system with smart sensors for resource-constrained cyber-physical devices and ...
Taewoo Lee, Yumin Choi, Hyunbum Kim
doaj   +1 more source

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