Results 161 to 170 of about 555,379 (343)
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang+9 more
wiley +1 more source
Classification of ten-dimensional symmetric embeddings for the spatially flat Friedman model [PDF]
All possible variants of symmetric embedding of the metric of the spatially flat Friedman model into a ten-dimensional ambient space are analyzed. It is shown that only two such embeddings exist: the five-dimensional embedding found by Robertson in 1933 and a new eight-dimensional embedding proposed in this work.
arxiv
On the hypersurface sections of algebraic varieties embedded in a projective space [PDF]
Mieo Nishi, Yoshikazu Nakai
openalex +1 more source
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui+15 more
wiley +1 more source
The lattice of embedded subsets
In cooperative game theory, games in partition function form are real-valued function on the set of so-called embedded coalitions, that is, pairs $(S, )$ where $S$ is a subset (coalition) of the set $N$ of players, and $ $ is a partition of $N$ containing $S$.
openaire +6 more sources
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei+7 more
wiley +1 more source
An equivalence for the embeddings of cells in a 3-manifold [PDF]
Robert J. Daverman, W. T. Eaton
openalex +1 more source
Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu+6 more
wiley +1 more source
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel+3 more
wiley +1 more source