Results 161 to 170 of about 1,397,905 (314)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Towards Self-Adaptation in Real-Time, Networked Systems: Efficient Solving of System Constraints for Automotive Embedded Systems

, 2011
Marc Zeller, Christian Prehofer, Gereon Weiß, Dirk Eilers, Rudi Knorr   +4 more
openalex   +2 more sources

The entanglement dynamics of interacting qubits embedded in a spin environment with Dzyaloshinsky-Moriya term [PDF]

, 2010
W. L. You, Y. L. Dong
openalex   +1 more source

Embedding theorems for variable exponent fractional Sobolev spaces and an application

, 2021
Haikun Liu, Yongqiang Fu
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Fresnel Lens with Embedded Vortices [PDF]

, 2011
Sunil Vyas, Rakesh Kumar Singh, Devinder Pal Ghai, P. Senthilkumaran   +3 more
openalex   +1 more source

Enhancing the practice of medicine with embedded multi-disciplinary researchers in a model of change

, 2021
Claire Neal, Marissa L. Shuffler, Riley Pegram, Sarah B. Floyd, Ann Blair Kennedy, Thomas W. Britt, Andrew W. Albano, Windsor Westbrook Sherrill, Donald W. Wiper, Desmond P. Kelly   +9 more
openalex   +1 more source

Isometric embeddings [PDF]

Bulletin of the American Mathematical Society, 1969
openaire   +3 more sources

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source