Results 101 to 110 of about 6,473,960 (319)
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah +7 more
wiley +1 more source
Time-Scale Invariant Audio Data Embedding
We propose a novel algorithm for high-quality data embedding in audio. The algorithm is based on changing the relative length of the middle segment between two successive maximum and minimum peaks to embed data.
Mansour Mohamed F, Tewfik Ahmed H
doaj +1 more source
DVNE-DRL: dynamic virtual network embedding algorithm based on deep reinforcement learning. [PDF]
Xiao X.
europepmc +1 more source
A Novel Optimal Mapping Algorithm With Less Computational Complexity for Virtual Network Embedding
Network virtualization (NV) is widely accepted as one enabling technology for future network, which enables multiple virtual networks (VNs) with different paradigms and protocols to coexist on the shared substrate network (SN). One key challenge in NV is
Haotong Cao +3 more
semanticscholar +1 more source
Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz +11 more
wiley +1 more source
Virtual Network Embedding Based on Topology Potential
To improve the low acceptance ratio and revenue to cost ratio caused by the poor match between the virtual nodes and the physical nodes in the existing virtual network embedding (VNE) algorithms, we established a multi-objective optimization integer ...
Xinbo Liu, Buhong Wang, Zhixian Yang
doaj +1 more source
Objective In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently, and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of the trajectory of a ...
Ji Soo Kim +18 more
wiley +1 more source
PGAGP: Predicting pathogenic genes based on adaptive network embedding algorithm. [PDF]
Zhang Y, Xiang J, Tang L, Yang J, Li J.
europepmc +1 more source

