Results 51 to 60 of about 102,869 (305)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Integrating and evaluating neural word embeddings in information retrieval [PDF]

open access: yes, 2015
Recent advances in neural language models have contributed new methods for learning distributed vector representations of words (also called word embeddings). Two such methods are the continuous bag-of-words model and the skipgram model.
Bevan Koopman   +7 more
core   +2 more sources

Systèmes dynamiques algébriquement complètement intégrables et géométrie

open access: yesAnnals of the West University of Timisoara: Mathematics and Computer Science, 2015
In this paper I present the basic ideas and properties of the complex algebraic completely integrable dynamical systems. These are integrable systems whose trajectories are straight line motions on complex algebraic tori (abelian varieties). We make, via
Lesfari A.
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Canonical Embeddings [PDF]

open access: yesTransactions of the American Mathematical Society, 1980
In this paper the authors compare the embedding of a compact Riemann surface in its tangent bundle to the embedding as the diagonal in the product. These embeddings are proved to be first, but not second, order equivalent. The embedding of a hyperelliptic curve in its tangent bundle is described in an explicit way.
Morrow, J., Rossi, H.
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Explore FREDDY: Fast Word Embeddings in Database Systems

open access: yes, 2019
Word embeddings encode a lot of semantic as well as syntactic features and therefore are useful in many tasks especially in Natural Language Processing and Information Retrieval.
Thiele, Maik   +3 more
core   +1 more source

Node Embeddings via Neighbor Embeddings

open access: yesTrans. Mach. Learn. Res.
Accepted to Transactions of Machine Learning Research (TMLR)
Jan Niklas Böhm   +5 more
openaire   +5 more sources

SemOpenAlex Embeddings

open access: yes, 2023
<p>Here, we provide knowledge graph embeddings for <a href="https://semopenalex.org">SemOpenAlex</a>.</p> <p>After conducting experiments using different knowledge graph embedding algorithms, including TransE, DistMult ...
Färber, Michael, Krause, Johan
core   +2 more sources

Optimised Data Integration using Transformer Model and Resource Description Framework

open access: yesJournal of Informatics and Web Engineering
Organizations have become highly reliant on a range of data sources that span structured, semi-structured, and unstructured data types. These repositories allow large-scale storage for faster ingestion and analytics but pose tremendous challenges of ...
Jerome Aondongu Achir   +2 more
doaj   +1 more source

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