Results 1 to 10 of about 3,522,304 (109)

US-align: universal structure alignments of proteins, nucleic acids, and macromolecular complexes

open access: yesNature Methods, 2022
Structure comparison and alignment are of fundamental importance in structural biology studies. We developed the first universal platform, US-align, to uniformly align monomer and complex structures of different macromolecules—proteins, RNAs and DNAs ...
Chengxin Zhang   +3 more
semanticscholar   +1 more source

Screening for Lung Cancer: US Preventive Services Task Force Recommendation Statement.

open access: yesJournal of the American Medical Association (JAMA), 2021
Importance Lung cancer is the second most common cancer and the leading cause of cancer death in the US. In 2020, an estimated 228 820 persons were diagnosed with lung cancer, and 135 720 persons died of the disease.
A. Krist   +18 more
semanticscholar   +1 more source

The All of Us Research Program: Data quality, utility, and diversity

open access: yesPatterns, 2022
Summary The All of Us Research Program seeks to engage at least one million diverse participants to advance precision medicine and improve human health. We describe here the cloud-based Researcher Workbench that uses a data passport model to democratize ...
Andrea H. Ramirez   +157 more
semanticscholar   +1 more source

Prevalence of Depression Symptoms in US Adults Before and During the COVID-19 Pandemic

open access: yesJAMA Network Open, 2020
Key Points Question What is the burden of depression symptoms among US adults during the coronavirus disease 2019 (COVID-19) pandemic compared with before COVID-19, and what are the risk factors associated with depression symptoms?
Catherine K. Ettman   +5 more
semanticscholar   +1 more source

COVID-19 pandemic, oil prices, stock market, geopolitical risk and policy uncertainty nexus in the US economy: Fresh evidence from the wavelet-based approach

open access: yesInternational Review of Financial Analysis, 2020
In this paper, we analyze the connectedness between the recent spread of COVID-19, oil price volatility shock, the stock market, geopolitical risk and economic policy uncertainty in the US within a time-frequency framework.
Arshian Sharif, C. Aloui, L. Yarovaya
semanticscholar   +1 more source

The "All of Us" Research Program.

open access: yesNew England Journal of Medicine, 2019
Knowledge gained from observational cohort studies has dramatically advanced the prevention and treatment of diseases. Many of these cohorts, however, are small, lack diversity, or do not provide comprehensive phenotype data.
J. Denny   +6 more
semanticscholar   +2 more sources

US Health Care Spending by Payer and Health Condition, 1996-2016.

open access: yesJournal of the American Medical Association (JAMA), 2020
Importance US health care spending has continued to increase and now accounts for 18% of the US economy, although little is known about how spending on each health condition varies by payer, and how these amounts have changed over time.
J. Dieleman   +21 more
semanticscholar   +1 more source

Robots and Jobs: Evidence from US Labor Markets

open access: yesJournal of Political Economy, 2019
We study the effects of industrial robots on US labor markets. We show theoretically that robots may reduce employment and wages and that their local impacts can be estimated using variation in exposure to robots—defined from industry-level advances in ...
Daron Acemoglu, P. Restrepo
semanticscholar   +1 more source

U.S. Monetary Policy and the Global Financial Cycle

open access: yesThe Review of Economic Studies, 2020
U.S. monetary policy shocks induce comovements in the international financial variables that characterize the “Global Financial Cycle.” A single global factor that explains an important share of the variation of risky asset prices around the world ...
Silvia Miranda-Agrippino, Hélène Rey
semanticscholar   +1 more source

«Paine pour joie». La divisa de Pere de Portugal, un príncep de la tardana edat mitjana [PDF]

open access: yes, 2020
Les divises van sorgir a finals del segle XIV amb l?objectiu de superar les limitacions del sistema heràldic, subjecte a un codi massa rígid i concebut exclusivament per traslladar conceptes dinàstics i de llinatge. Aquest estudi proposa una dissecció de
Molina, Juan
core   +1 more source

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