Results 71 to 80 of about 121,407 (260)

A Second Pathogenic Protein, PolyGN2C‐iso2, Reveals a Dual‐Protein Pathology in Neuronal Intranuclear Inclusion Disease

Advanced Science, EarlyView.
This study reveals that NOTCH2NLC transcript variant 2 generates PolyGN2C‐iso2, an aggregating protein present within intranuclear inclusions of NIID patient tissues. A novel mouse model expressing PolyGN2C‐iso2 recapitulates white matter abnormalities and cognitive deficits, mechanistically linked to mitochondrial dysfunction. These findings support a
Kang Zhang, Wenhao Ma, Yi Zhou, Zhijie Wu, Pan Gao, Hongze Niu, Hongfei Tai, Tianyi Zhao, Zheyue Dong, Li Li, Yan Zhang, An Wang, Si Shen, Yueyang Li, Sifei Yu, Yan Peng, Wang Sheng, Xiaoyan Dong, Hua Pan, Kaibin Shi, Magdalena J. Koziol, Xiaobing Wu, Zaiqiang Zhang   +22 more
wiley   +1 more source

Women’s Cultural Capital, Care Work Burden and Career Outcomes in Vietnam’s Creative Economy: A Cross-Generational Study

Journal of economics, finance and management studies
In Vietnam’s rapidly expanding creative economy, women face unique challenges balancing professional aspirations with persistent caregiving responsibilities shaped by social and cultural norms.
Quan Nguyen Van, Thúy Anh
semanticscholar   +1 more source

Modulating Calcium Homeostasis via a Biomimetic Scaffold to Rescue Diabetic Ischemic Wounds

Advanced Science, EarlyView.
This strategy addresses impaired microcirculation and loss of extracellular matrix (ECM) guidance in diabetic wound healing. Musc@CP, a nanofibrous dressing combining an ECM‐mimetic chitosan‐pullulan scaffold with muscone, enhances perfusion by attenuating intracellular Ca2+ overload‐associated endothelial dysfunction.
Xiang Zheng, Mingmei Li, Jianjun Jiang, Yongchao Wang, Yaru Jia, Weilun Sun, Yi Yao, Pengli Gao, Linhua Zhang, Qi Guo, Guang Jia, Xing‐Jie Liang, Dunwan Zhu, Jinchao Zhang, Fangzhou Li   +14 more
wiley   +1 more source

Engineering a 660 nm‐Responsive Optogenetic Inducer of Pyroptosis for Precision Cancer Therapy

Advanced Science, EarlyView.
This study reports a bioorthogonal pyroptosis inducer, PyroRACS. By using a red‐light‐responsive Cre‐On genetic switch to control the expression of highly cytotoxic GSDMDNT, PyroRACS enables the artificial induction of pyroptosis with precise spatiotemporal control.
Mengkai Zhang, Zhichao Li, Yonghao Ma, Yangyang Sun, Wei Chen, Weiren Huang   +5 more
wiley   +1 more source

Private school entry to Oxbridge: how cultural capital counts in the making of elites

British Journal of Sociology of Education
In this article we make an argument for the importance of embodied cultural capital in the generation of class advantage through private school students’ access to Oxbridge.
Rachel Louise Stenhouse, Nicola Ingram
semanticscholar   +1 more source

Differentiated Impacts of EU Rural Development Measures: A Finite Mixture Evaluation of Italian Olive Farms

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT This paper examines the relationship between participation in the EU Rural Development Program and the economic performance of Italian olive farms using a finite‐mixture model with inverse‐probability‐weighted regression adjustment. Based on 2010–2022 FADN panel data, it estimates heterogeneous treatment effects while correcting for selection ...
Francesco Caracciolo, Marilena Furno
wiley   +1 more source

Breastfeeding selfies as relational practice: becoming a maternal subject in the digital age: a single case study

International Breastfeeding Journal, 2019
Background In 2015, the popular online parenting forum, Netmums, named breastfeeding selfies as the number one parenting trend in the UK for that year.
Sharon Tugwell
doaj   +1 more source

Advancing Stratification Research by Measuring Non-declarative Cultural Capital: A National Population-Based Study Combining IAT and Survey Data

American Sociological Review
Cultural capital is a central concept in stratification research. Crucial to the Bourdieusian habitus, upper strata familiarity with the dominant culture is assumed to be ingrained via socialization, allowing its members to smoothly navigate educational ...
Jeroen van der Waal, W. de Koster, T. van Meurs, K. Noordzij, J. O. Groeniger, Julian Schaap   +5 more
semanticscholar   +1 more source

Heavy Metal Contamination: Impacts From Plants to the Food Chain and Eco‐Friendly Amelioration Strategies

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Heavy metal pollution reduces soil health and threatens food safety by entering plants; however, the use of nanoparticles, biofertilizers, and organic fertilizers such as biochar offers a promising strategy for improvement and sustainable agriculture. ABSTRACT Heavy metal (HM) pollution, resulting from human activities such as mining and the excessive ...
Sina Siavash Moghaddam, Latifeh Pourakbar, Sevda Alizadeh, Zahra Alizadeh, Jelena Popović‐Djordjević   +4 more
wiley   +1 more source

Regarding Symbolic Capital: Poetry Translators from Modern Greek into English

Hermes, 2018
   The research object of this study is the symbolic capital of poetry translators and how it shapes and is being shaped by the current practices and self-descriptions of translators of Modern Greek poetry into English.
Nadia Georgiou
doaj   +1 more source