Results 51 to 60 of about 35,572 (277)

Comparison of clinical signs and outcomes between dogs with presumptive ischemic myelopathy and dogs with acute non compressive nucleus pulposus extrusion [PDF]

, 2016
OBJECTIVE To compare clinical signs and outcomes between dogs with presumptive ischemic myelopathy and dogs with presumptive acute noncompressive nucleus pulposus extrusion (ANNPE). DESIGN Retrospective study. ANIMALS 51 dogs with ischemic myelopathy and
De Decker, S, Drees, R, Fenn, J T, Volk, H A   +3 more
core   +2 more sources

Fat Embolism

Critical Care and Resuscitation, 1999
To review the pathophysiology and management of patients with clinical manifestations of fat embolism.A review of studies reported from 1976 to 1998 and identified through a MEDLINE search of the literature on fat embolism and fat embolism syndrome.Fat embolism occurs when bony or soft tissue trauma has caused fat to enter the circulation, or in ...
P, Glover, L I, Worthley
openaire   +2 more sources

METTL14‐Mediated M6A Modification of LINC01094 Induces Glucose Metabolic Reprogramming in Breast Cancer by Recruiting the PKM2/JMJD5 Complex

Advanced Science, EarlyView.
METTL14/IGF2BP2‐mediated m6A modification drives LINC01094 upregulation in BC. Then, LINC01094 interacts with PKM2 monomers to promote their dimerization, while serving as a flexible scaffold to facilitate the assembly of the PKM2/JMJD5 complex, synergistically stabilizing PKM2 dimers and enhancing their nuclear translocation.
Mengqi Wang, Zhaoxin Gao, Ruinan Zhao, Pan Zhou, Jingxi Chen, Hui Zhang, Yawen Wang, Wenjie Zhu, Peng Gao   +8 more
wiley   +1 more source

MYC/TET3‐Regulated TMEM65 Activates OXPHOS‐SERPINB3 Pathway to Promote Progression and Cisplatin Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer (TNBC) remains a major challenge in breast cancer management as it lacks effective therapeutic targets. This study uncovers that MYC/TET3‐regulated mitochondrial inner‐membrane protein TMEM65 promotes TNBC progression and cisplatin resistance by activating the OXPHOS‐SERPINB3 pathway and reveals TMEM65 as a potential ...
Yin‐Ling Zhang, Min‐Ying Huang, Shao‐Ying Yang, Jia‐Yang Cai, Qian Zhao, Fang‐Lin Zhang, Xin Hu, Zhi‐Min Shao, Li Liao, A‐Yong Cao, Da‐Qiang Li   +10 more
wiley   +1 more source

Síndrome da angústia respiratória do adulto por embolia gordurosa no período pós-operatório de lipoaspiração e lipoenxertia Adult respiratory distress syndrome due to fat embolism in the postoperative period following liposuction and fat grafting

Jornal Brasileiro de Pneumologia, 2008
A embolia gordurosa é definida como a ocorrência de bloqueio mecânico da luz vascular por gotículas circulantes de gordura. Acomete principalmente o pulmão, podendo afetar também o sistema nervoso central, a retina e a pele.
André Nathan Costa, Daniel Melo Mendes, Carlos Toufen, Gino Arrunátegui, Pedro Caruso, Carlos Roberto Ribeiro de Carvalho   +5 more
doaj   +1 more source

Fat embolism syndrome in patients with bilateral femur fractures: a systematic review and case comparison

OTA International, 2022
. Objectives:. Fat embolism and fat embolism syndrome (FES) remain common complications following long bone fractures. Incidence is highest after bilateral femur fractures.
Yannik Kalbas, MD, Thomas Seaver, MD, Yohei Kumabe, MD, Sascha Halvachizadeh, MD, Maximilian Lempert, MD, Roman Pfeifer, PD MD, Andrew Marcantonio, DO MBA, Hans-Christoph Pape, MD   +7 more
doaj   +1 more source

Single‐Cell RNA Sequencing Delineates Renal Anti‐Fibrotic Mechanisms Mediated by TRPC6 Inhibition

Advanced Science, EarlyView.
Single‐cell transcriptomics reveals how TRPC6 inhibition alters renal cell composition and gene expression in CKD. The study uncovers a novel endothelial subpopulation (ECRIN), highlights key inflammatory and fibrotic pathways, and identifies a Prnp‐driven network linked to fibrosis resolution, offering mechanistic insight into TRPC6 as a potential ...
Yao Xu, Zhihuang Zheng, Marleen Silke Oswald, Guozhe Cheng, Jun Liu, Qidi Zhai, Ute Kruegel, Michael Schaefer, Holger Gerhardt, Nicole Endlich, Maik Gollasch, Stefan Simm, Dmitry Tsvetkov   +12 more
wiley   +1 more source

Interleukin-6 as an early marker for fat embolism

Journal of Orthopaedic Surgery and Research, 2009
Background Fat Embolism is a complication of long bone fractures, intramedullary fixation and joint arthroplasty. It may progress to fat embolism syndrome, which is rare but involves significant morbidity and can occasionally be fatal.
Yoga R, Theis JC, Walton M, Sutherland W
doaj   +1 more source

Nanomedicine‐Driven Modulation of Reductive Stress for Cancer Therapy

Advanced Science, EarlyView.
This article introduces a novel therapeutic paradigm that deliberately induces reductive stress within tumor cells to exploit their unique biochemical vulnerabilities. It systematically reviews the underlying biological mechanisms, current detection and monitoring techniques, and emerging advanced nanotechnology platforms specifically designed to ...
Yumin Mao, Xianping Liu, Xu Chu, Feixiang Chen, Ruicheng Shi, Zonghao Liu, Yelin Wu, Yanyan Liu, Wenbo Bu   +8 more
wiley   +1 more source

Delayed onset of fat embolus in the cerebral venous system after breast and hip augmentation: a case report

BMC Neurology, 2021
Background Cerebral fat embolism (CFE) is a subtype of fat embolism syndrome which tends to cause ischemic cerebral infarction. Fat embolism in the cerebral venous system have not been reported.
Wei Dong, Ding-yuan Wan, Xiang Yang, Min Fu, Xing Liu, Hao Li, Xiao-qi Xie   +6 more
doaj   +1 more source