Results 91 to 100 of about 9,087 (227)

Impending paradoxical embolism. When and how to treat? [PDF]

, 2008
Impending paradoxical embolism (IPDE) is the presence of an entrapped thrombus through the patent foramen ovale (PFO). Usually IPDE are diagnosed by echocardiography or thoracic CT-scan performed during the evaluation of patient presenting with a ...
Myers, Patrick-Olivier, Boehlen, Françoise, Robert-Ebadi, Helia, Righini, Marc Philip, Fassa, A., Fontana, Pierre, Bonvini, Robert, Licker, Marc   +7 more
core   +1 more source

Cardiotoxicity of BRAF/MEK inhibitors

British Journal of Pharmacology, EarlyView.
Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe, Valerie Lohner, Kevin Terre, Thomas Riffelmacher, Roman Pfister   +4 more
wiley   +1 more source

Pulmonary Thromboembolism in a Patent With Patent Foramen Ovale

Case Reports in Clinical Practice, 2019
During the recent years, paradoxical embolism and Patent Foramen Ovale (PFO) have drawn great attention because of their strong correlation with cryptogenic stroke in young patients.
Behshad Pazooki, Hanieh Radkhah, Alborz Sherafati   +2 more
doaj  

Impending paradoxical embolism: systematic review of prognostic factors and treatment [PDF]

, 2010
BACKGROUND: Little is known about the optimal management of impending paradoxical embolism (IPDE), a biatrial thromboembolus caught in transit across a patent foramen ovale.
Lerch, René, Myers, Patrick Olivier, Panos, Aristotelis, Bounameaux, Henri, Kalangos, Afksendiyos   +4 more
core   +1 more source

Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease

Cell Proliferation, EarlyView.
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik, Muhammad Dilawar, Junguang Liao, Jie Zheng, Qitao Qian, Ming Xu, Sisi Lin, Xiaobo Zhu, Qiuwei Ge, Limin Jin, Guiqian Chen   +10 more
wiley   +1 more source

Paradoxical embolism entrapped in a patent foramen ovale [PDF]

, 2023
Background: According to the Centers for Disease Control (CDC), venous thromboembolisms affect 900,000 people and cause up to 100,000 deaths yearly. A less common subset of these cases includes those of which the emboli, though originating in venous ...
Rowan, Macy, Seibolt, Lucas, Malik, Mohammad, Beaver, Barney   +3 more
core   +1 more source

Performing Large‐Scale Genetic Analysis in the Bleeding Disorders Community

Haemophilia, EarlyView.
ABSTRACT Inherited bleeding disorders encompass a diverse group of conditions caused by genetic defects affecting coagulation factors, fibrinogen, von Willebrand factor, or platelet function. Despite major advances in quantitative and functional laboratory assays, a substantial diagnostic gap remains, particularly in patients with mild or atypical ...
Anna R. Blankstein, Sterre P. E. Willems, Saskia E. M. Schols, Rosanna Asselta, Gillian Lowe, Neil V. Morgan, Paula D. James   +6 more
wiley   +1 more source

Cerebrovascular Accident Secondary to Paradoxical Embolism Following Arteriovenous Graft Thrombectomy [PDF]

, 2012
Thrombectomy is a common procedure performed to declot thrombosed dialysis arteriovenous fistula (AVF) or arteriovenous graft (AVG). Complications associated with access thrombectomy like pulmonary embolism have been reported, but paradoxical embolism is
Jolina Pamela Santos, Naheed Ansari, Zaher Hamadeh   +2 more
core   +1 more source

Associations Between Weight Loss Prior to Knee and Hip Arthroplasty and Peri‐ and Post‐Operative Outcomes: A Systematic Review and Meta‐Analysis

Obesity Reviews, EarlyView.
ABSTRACT Background In some of the existing literature, obesity is associated with increased complications in those who undergo lower limb arthroplasty. We conducted a systematic review and meta‐analysis to assess if pre‐arthroplasty weight loss mitigates increased post‐operative risks. Methods This systematic review and meta‐analysis was registered on
Moneet Gill, Tim Lindsay, Daniel Kevin Llanera, Tricia M.‐M. Tan, Alex Liddle, Chioma Izzi‐Engbeaya   +5 more
wiley   +1 more source

Acute ECG ST-segment elevation mimicking myocardial infarction in a patient with pulmonary embolism

Cardiovascular Ultrasound, 2010
Pulmonary embolism is a common cardiovascular emergency, but it is still often misdiagnosed due to its unspecific clinical symptoms. Elevated troponin concentrations are associated with greater morbidity and mortality in patients with pulmonary embolism.
Podbregar Matej, Goslar Tomaž
doaj   +1 more source