Results 231 to 240 of about 378,039 (360)

Doxorubicin‐Loaded Metal–Organic Framework for Ferroptosis‐Enhanced Chemotherapy Through Sustained Zn Release and Glutathione Peroxidase Downregulation

Advanced Healthcare Materials, EarlyView.
A robust zinc‐based metal–organic framework (ZnMOF) enables dual functions of doxorubicin delivery and sustained Zn2+ release to trigger ferroptosis‐enhnaced chemotherapy. DOX@ZnMOF effectively depletes intracellular glutathione, suppresses GPX4, and elevates reactive oxygen species, leading to efficient oxidative DNA damage and apoptosis.
Xin Ma, Chenghua Deng, Chaoyu Wang, Langston Tilman, Jinhong Li, Wenbin Lin   +5 more
wiley   +1 more source

A novel predictor of short-term prognosis in acute pulmonary embolism: inflammatory burden index. [PDF]

Ther Adv Cardiovasc Dis
Huang L, Xiao D, Yang M, Wu Z, He F.
europepmc   +1 more source

The rationale, design, and methods of a randomized, controlled trial to evaluate the efficacy and safety of an active strategy for the diagnosis and treatment of acute pulmonary embolism during exacerbations of chronic obstructive pulmonary disease [PDF]

, 2019
et al,, SLICE investigators,, Yusen, Roger   +2 more
core   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Association of Shock Index and Variants with Mortality in Acute Pulmonary Embolism. [PDF]

West J Emerg Med
Upchurch CP, Sanfilippo K, Lew D, Samant M, McDonald R.   +4 more
europepmc   +1 more source

Micro-CT: a technology for direct visualisation and quantification in plant ecophysiology [PDF]

, 2015
De Baerdemaeker, Niels, Steppe, Kathy, Van Camp, Janne, Vergeynst, Lidewei   +3 more
core   +1 more source

Life-threatening pulmonary embolism seen as hyperdense clots on unenhanced CT

Ana Paula Zanardo, Rafael Domingos Grando, Rafael Ramos Rambo   +2 more
openalex   +1 more source

Clinical Characteristics and Prognosis of Acute Pulmonary Embolism with Hemoptysis in Autoimmune Disease Patients [PDF]

Yiyao Li, Jianian Yang, Peijun Xue, Ting Zhang, Xuefeng Sun, Min Peng, Juhong Shi   +6 more
openalex   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Massive Air Embolism in the Pulmonary Artery During Permanent Pacemaker Insertion. [PDF]

Cureus
Chopra N, Mehta K, Ansari A, Singh SK, Kumar D.   +4 more
europepmc   +1 more source