Results 41 to 50 of about 250,030 (316)

Diagnostic Role of Multi-Detector Computed Tomography in Acute Mesenteric Ischemia

open access: yesDiagnostics
Mesenteric ischemia diagnosis is challenging, with an overall mortality of up to 50% of cases despite advances in treatment. The main problem that affects the outcome is delayed diagnosis because of non-specific clinical presentation.
Francesco Michele Ronza   +12 more
doaj   +1 more source

Prognosis of Acute Intracranial Atherosclerosis-Related Occlusion after Endovascular Treatment [PDF]

open access: yesJournal of Stroke, 2018
Background and Purpose Little is known about prognosis after endovascular therapy (EVT) for acute large artery occlusion (LAO) caused by underlying intracranial atherosclerotic stenosis (ICAS).
Jin Soo Lee   +13 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Cerebral microembolization in patients with prosthetic valve and anticoagulation assessment using transcranial Doppler ultrasonography

open access: yesAl-Azhar Assiut Medical Journal, 2018
Background Transcranial Doppler detection of microemboli is widely described, and thromboembolism is a major cause of morbidity in patients with prosthetic heart valves. They require lifelong anticoagulation to minimize thrombotic complications.
Mohamed A Zaki, Mohamed EL Sayed Moussa
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

CT Guided Removal of Iatrogenic Foreign Body: A Broken Intravenous Cannula [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2015
Foreign bodies are encountered on day to day basis by a surgeon. Usually foreign bodies are lodged in narrow cavities of the body and the common age group is in children.
Amanpreet Singh   +3 more
doaj   +1 more source

Extensive Pulmonary Embolism in late pregnancy associated with Anticardiolipin Antibodies [PDF]

open access: yes, 2004
The leading cause of morbidity and mortality during pregnancy and the puerperium is venous thromboembolism. Though uncommon, the risk is five times higher in a pregnant woman than in a non-pregnant woman of similar age.1,2 In pregnancy, all three ...
Brincat, Mark P.   +5 more
core  

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk   +10 more
wiley   +1 more source

A real dilemma: Management of multiple mycotic visceral aneurysms revealing severe endocarditis

open access: yesIndian Journal of Vascular and Endovascular Surgery, 2018
We present a case of endocarditis, which manifested as an acute-onset of abdominal pain, due to multiple mycotic visceral aneurysms in a 31-year-old man. We initially thought that the pain had a surgical visceral aetiology.
Zahira Zouizra   +4 more
doaj   +1 more source

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