Results 211 to 220 of about 126,101 (317)

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

open access: yesThe FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin   +2 more
wiley   +1 more source

Management of Breakthrough Bleeding During Emicizumab Prophylaxis in Acquired Haemophilia A: Data From the GTH‐AHA‐EMI Study

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction The GTH‐AHA‐EMI study showed that emicizumab reduces bleeding in patients with acquired haemophilia A (AHA). However, 22 clinically relevant new bleeds (CRNB) occurred in 14 of the 47 study patients, most of which required haemostatic treatment.
Halet Türkantoz   +11 more
wiley   +1 more source

Zero‐Contrast Versus Contrast‐Guided Left Atrial Appendage Occlusion: A Comparative Analysis of Procedural and Long‐Term Outcomes

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
Zero‐contrast left atrial appendage occlusion yielded high procedural success and similar periprocedural adverse event rates compared to the contrast‐guided approach. At 45‐day follow‐up, successful LAA closure (defined as peri‐device leak ≤ 5 mm) and device‐related thrombus rates were similar.
Joe Demian   +12 more
wiley   +1 more source

Balloon-occluded Retrograde Transvenous Obliteration for Gastric Varices Draining into the Gastrocaval Shunt. [PDF]

open access: yesInterv Radiol (Higashimatsuyama)
Miyayama S   +5 more
europepmc   +1 more source

Implementation of a Standardized Nurse‐Guided Heparinization Protocol Improves Anticoagulation During Left Atrial Ablation Procedures

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
A standardized, nurse‐led heparinization protocol significantly improves the speed, consistency, and precision of achieving therapeutic ACT levels during left atrial ablation, while reducing excessive anticoagulation and maintaining a comparable safety profile to conventional operator‐guided dosing.
Vanessa Sciacca   +14 more
wiley   +1 more source

Temperate tree species show cross‐tolerance to heat, drought, and late spring‐frost stress

open access: yesNew Phytologist, EarlyView.
Significant cross‐tolerance of leaf traits to heat, drought and late spring‐frost were found. (a) Turgor loss point vs lethal spring‐frost temperature. (b) Heat thermal threshold temperature vs lethal spring‐frost temperature. (c) Heat thermal threshold temperature vs turgor loss point.
Norbert Kunert   +5 more
wiley   +1 more source

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