The late endocytic Rab39a GTPase regulates the interaction between multivesicular bodies and chlamydial inclusions. [PDF]
Given their obligate intracellular lifestyle, Chlamydia trachomatis ensure their access to multiple host sources of essential lipids by interfering vesicular transport.
Capmany, Anahi +7 more
core +1 more source
Abstract Neurospheres (NS) derived from adult stem cells of non‐neural tissues represent a promising source of neural stem cells (NSCs) and neural progenitor cells (NPCs) for autologous cell therapy. Knowing the fine structure of NS cells is essential for characterizing them during differentiation or oncogenic transformation.
Concepción Rojo Salvador +4 more
wiley +1 more source
Epac, Rap and Rab3 act in concert to mobilize calcium from sperm's acrosome during exocytosis [PDF]
BACKGROUND: Exocytosis of sperm's single secretory granule or acrosome (acrosome reaction, AR) is a highly regulated event essential for fertilization. The AR begins with an influx of calcium from the extracellular milieu and continues with the synthesis
Bustos, Matias Alberto +3 more
core +1 more source
Changes in renal WT-1 expression preceding hypertension development [PDF]
Background: Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information.
Abud, María Angélica +8 more
core +2 more sources
Contribution of microscopy for understanding the mechanism of action against trypanosomatids [PDF]
Transmission electron microscopy (TEM) has proved to be a useful tool to study the ultrastructural alterations and the target organelles of new antitrypanosomatid drugs.
A Martinez-Palomo +90 more
core +1 more source
Controllability of protein-protein interaction phosphorylation-based networks: Participation of the hub 14-3-3 protein family [PDF]
Posttranslational regulation of protein function is an ubiquitous mechanism in eukaryotic cells. Here, we analyzed biological properties of nodes and edges of a human protein-protein interaction phosphorylation-based network, especially of those nodes ...
Bustos, Diego Martin +2 more
core +1 more source
Functional hypothesis of the juxtaoral organ: Role of collagen types I and III
Oral Diseases, Volume 29, Issue 1, Page 322-326, January 2023.
Antonio José Mérida‐García +8 more
wiley +1 more source
Circadian rhythms of proliferation events in two mouse carcinomas [PDF]
We studied the index of DNA synthesis (DNAs) of two cellular carcinomas: the hepatocellular ES12a and the mammary TN60 of mice, throughout one circadian cycle.
Andrini, Laura Beatríz +6 more
core +1 more source
Mesenchymal Stem Cell Therapy in Type 1 Diabetes Mellitus and Its Main Complications: From Experimental Findings to Clinical Practice [PDF]
Type 1 diabetes mellitus (T1DM) is a complex multifactorial disorder which involves a loss of self-tolerance leading to the autoimmune destruction of pancreatic β−cells.
Arango Rodriguez, Martha +3 more
core +1 more source
Natural Sesquiterpene Lactones Induce Oxidative Stress in Leishmania mexicana [PDF]
Leishmaniasis is a worldwide parasitic disease, caused by monoflagellate parasites of the genus Leishmania. In the search for more effective agents against these parasites, the identification of molecular targets has been attempted to ensure the ...
Barrera, Patricia Andrea +7 more
core +3 more sources

