Results 91 to 100 of about 779,274 (371)
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
Free energy of multicomponent embryo formation [PDF]
arXiv, 2002 An expression for the free energy of embryo formation is constructed and analyzed. The Gibbs dividing surfaces method is used to attain a coincidence between Laplace formula for critical embryo and integral definitions of concenterations inside the embryo. A global structure of free energy is analyzed and some useful properties are extracted.
arxiv
Automated Measurements of Key Morphological Features of Human Embryos for IVF [PDF]
arXiv, 2020 A major challenge in clinical In-Vitro Fertilization (IVF) is selecting the highest quality embryo to transfer to the patient in the hopes of achieving a pregnancy. Time-lapse microscopy provides clinicians with a wealth of information for selecting embryos.
arxiv
Outward Migration of Terrestrial Embryos in Binary Systems [PDF]
, 2009 We consider the formation and migration of protoplanetary embryos in disks around the stars in tight binary systems (separations ~ 20 AU. In such systems, the initial stages of runaway embryo formation are expected to only take place within some critical disk radius a_{crit}, due to the perturbing effect of the binary companions (Thebault et al. 2009).
arxiv +1 more source
FEBS Open Bio, EarlyView.IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He +5 more
wiley +1 more source
Revista Científica, 2023 Somatic cell nuclear transfer (SCNT) has emerged as a valuable assisted reproductive technology for faster multiplication of animals. This helps to preserve the valuable superior germplasm.
Tanya Gupta +4 more
doaj
Modeling the Formation of Giant Planet Cores I: Evaluating Key Processes [PDF]
, 2009 One of the most challenging problems we face in our understanding of planet formation is how Jupiter and Saturn could have formed before the the solar nebula dispersed. The most popular model of giant planet formation is the so-called 'core accretion' model. In this model a large planetary embryo formed first, mainly by two-body accretion. This is then
arxiv +1 more source
Embryo metabolism : what does it really mean? [PDF]
, 2015 The study of early embryo metabolism has fascinated researchers in the field for nearly a century. Herein, we give a brief account of the general features of embryo metabolism and some consideration of the research performed to reach such conclusions. It
Lewis, Niamh, Sturmey, Roger
core
Modeling mammalian gastrulation with embryonic stem cells
, 2017 Understanding cell fate patterning and morphogenesis in the mammalian embryo remains a formidable challenge. Recently, in vivo models based on embryonic stem cells (ESCs) have emerged as complementary methods to quantitatively dissect the physical and ...
Amita +65 more
core +1 more source