Results 111 to 120 of about 806,752 (380)
Accretion of Uranus and Neptune from inward-migrating planetary embryos blocked by Jupiter and Saturn [PDF]
Reproducing Uranus and Neptune remains a challenge for simulations of solar system formation. The ice giants' peculiar obliquities suggest that they both suffered giant collisions during their formation. Thus, there must have been an epoch of accretion dominated by collisions among large planetary embryos in the primordial outer solar system.
arxiv +1 more source
Possible role of human ribonuclease dicer in the regulation of R loops
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik+2 more
wiley +1 more source
Bmp4 is required for the generation of primordial germ cells in the mouse embryo.
In many organisms the allocation of primordial germ cells (PGCs) is determined by the inheritance of maternal factors deposited in the egg. However, in mammals, inductive cell interactions are required around gastrulation to establish the germ line. Here,
K. Lawson+7 more
semanticscholar +1 more source
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei+7 more
wiley +1 more source
Time to take human embryo culture seriously.
STUDY QUESTION Is it important that end-users know the composition of human embryo culture media? SUMMARY ANSWER We argue that there is as strong case for full transparency concerning the composition of embryo culture media intended for human use ...
A. Sunde+7 more
semanticscholar +1 more source
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren+8 more
wiley +1 more source
Correction After publication of the original article [1] it was noted that the caption of Table two was incorrect. This caption should read “Distribution of ovarian follicles depending on the type (healthy, transitional, and atretic) Small superscript ...
Emilia Sinderewicz+6 more
doaj +1 more source
Atlas-based automated detection of swim bladder in Medaka embryo [PDF]
Fish embryo models are increasingly being used both for the assessment of chemicals efficacy and potential toxicity. This article proposes a methodology to automatically detect the swim bladder on 2D images of Medaka fish embryos seen either in dorsal view or in lateral view. After embryo segmentation and for each studied orientation, the method builds
arxiv
Deep learning mediated single time-point image-based prediction of embryo developmental outcome at the cleavage stage [PDF]
In conventional clinical in-vitro fertilization practices embryos are transferred either at the cleavage or blastocyst stages of development. Cleavage stage transfers, particularly, are beneficial for patients with relatively poor prognosis and at fertility centers in resource-limited settings where there is a higher chance of developmental failure in ...
arxiv
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu+6 more
wiley +1 more source