Results 141 to 150 of about 805,032 (333)

Actomyosin polarisation through PLC-PKC triggers symmetry breaking of the mouse embryo

open access: yesNature Communications, 2017
The molecular trigger that establishes cell polarity in the mammalian embryo is unclear. Here, the authors show that de novo polarisation of the mouse embryo at the 8-cell stage is directed by Phospholipase C and Protein kinase C and occurs in two phases:
Meng Zhu   +3 more
doaj   +1 more source

Embryo staging with weakly-supervised region selection and dynamically-decoded predictions [PDF]

open access: yesarXiv, 2019
To optimize clinical outcomes, fertility clinics must strategically select which embryos to transfer. Common selection heuristics are formulas expressed in terms of the durations required to reach various developmental milestones, quantities historically annotated manually by experienced embryologists based on time-lapse EmbryoScope videos.
arxiv  

Ultra‐Effective Light‐Activated Antibacterial Activity via Carboxyl Functionalized Graphene Quantum Dots and Films

open access: yesAdvanced Functional Materials, EarlyView.
Carboxyl‐functionalized graphene quantum dots (cGQDs) exhibit high singlet oxygen quantum yield due to strong spin–orbit coupling. cGQDs achieve minimum bactericidal concentration of only 0.4 µg mL−1 against S. aureus under low‐intensity illumination.
Muhammad Hassnain   +10 more
wiley   +1 more source

Multi-Task Deep Learning with Dynamic Programming for Embryo Early Development Stage Classification from Time-Lapse Videos [PDF]

open access: yesarXiv, 2019
Time-lapse is a technology used to record the development of embryos during in-vitro fertilization (IVF). Accurate classification of embryo early development stages can provide embryologists valuable information for assessing the embryo quality, and hence is critical to the success of IVF.
arxiv  

Biointerfacing with AgBiS2 Quantum Dots for Pseudocapacitive Photostimulation

open access: yesAdvanced Functional Materials, EarlyView.
It is demonstrated that AgBiS2 quantum dots exhibit unique photoinduced pseudocapacitive charge transfer properties, enabling efficient light‐to‐electrical energy conversion. These quantum dots facilitate enhanced light absorption and transduction when integrated with ZnO nanowires, which serve as an effective charge transport medium.
Ridvan Balamur   +8 more
wiley   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

open access: yesAdvanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim   +8 more
wiley   +1 more source

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