The study deciphers the landscapes of lineage‐related transcription factors in prostatic adenocarcinoma and neuroendocrine prostate cancer using an innovative approach. These findings, validated across cohorts, highlight TFs' roles in cell development and offer novel therapeutic targets.
Yu Wang+20 more
wiley +1 more source
Three-dimensional exploration of the chicken embryo, a comparative study of light sheet and histological visualisation. [PDF]
Smallridge MW+8 more
europepmc +1 more source
The development of the mucous membrane of the large intestine and vermiform process in the human embryo [PDF]
Franklin P. Johnson
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The Placenta Regulates Intrauterine Fetal Growth via Exosomal PPARγ
The placenta expresses much higher levels of PPARγ than fetal adipose tissue. Trophoblastic exosomes transport PPARγ into fetal preadipocytes via fetoplacental circulation and thus regulate adipogenic genes distinct from endogenous PPARγ. Compromised placental PPARγ leads to fetal adipogenesis deficiency and intrauterine growth restriction, reversible ...
Xiaofang Luo+17 more
wiley +1 more source
Association between endometrial echo on transfer day and pregnancy outcomes in thawed embryo transfer: a retrospective cohort study across different preparation protocols. [PDF]
Run Z, Qianyan S, Xiaofang L.
europepmc +1 more source
Beschreibung eines menschlichen Embryos von 4:9 mm. [PDF]
N. William Ingalls
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In this study, the improvement effect of AMP on obesity can be attributed to the conversion of extracellular AMP to ADO through ADORA2A activation by CD73, which can promote lipolysis by reducing DNA methylation level and enhancing HSL gene transcription. These findings show the great potential of AMP in improving obesity.
Zhijuan Cui+12 more
wiley +1 more source
Successful birth after preimplantation genetic testing for rare mitochondrial DNA mutation m.10197G>A. [PDF]
Mizuguchi Y, Sueoka K, Sato S, Tanaka M.
europepmc +1 more source
The development of the mammalian jugular lymphsac, of the tributary primitive ulnar lymphatic and of the thoracic ducts from the view point of recent investigations of vertebrate lymphatic ontogeny, together with a consideration of the genetic relations of lymphatic and haemal vascular channels in the embryos of amniotes [PDF]
Geo. S. Huntington
openalex +1 more source