Results 321 to 330 of about 779,274 (371)

Simultaneous Detection of Neural Activity and Temperature in Photothermal Neural Stimulation

open access: yesAdvanced Science, EarlyView.
Photothermal neuromodulation technology faces limitations in understanding its mechanisms and effects on cellular behavior due to the difficulty of directly measuring temperature changes at the cell interface during optical stimulation of neurons. To overcome this challenge, ultrasensitive, transparent temperature sensors integrated with low‐noise ...
Duhee Kim   +8 more
wiley   +1 more source

Causes of embryo implantation failure: A systematic review and metaanalysis of procedures to increase embryo implantation potential. [PDF]

open access: yesFront Endocrinol (Lausanne)
Bulletti FM   +8 more
europepmc   +1 more source

From Invaginating Site to Deep Lesion: Spatial Transcriptomics Unravels Ectopic Endometrial Penetration Features in Adenomyosis

open access: yesAdvanced Science, EarlyView.
This work utilizes spatial transcriptomics to map the transcriptional landscape of adenomyosis with obvious invagination structure from the invaginating site to deep lesions. By integrating with single‐cell RNA sequencing, this study elucidates the molecular features of invagination, invasion, and fibrosis, and finds the major participants and vital ...
Boyu Li   +19 more
wiley   +1 more source

Dipeptidic Phosphonates: Potent Inhibitors of Pseudomonas aeruginosa Elastase B Showing Efficacy in a Murine Keratitis Model

open access: yesAdvanced Science, EarlyView.
A new series of highly potent dipeptidic phosphonates targeting the Pseudomonas aeruginosa protease LasB shows promising in vitro effects, favorable pharmacokinetics, good tolerability, and in vivo efficacy, highlighting their potential as a treatment for Pseudomonas keratitis when combined with meropenem. Abstract The ubiquitous opportunistic pathogen
Alexander F. Kiefer   +22 more
wiley   +1 more source

The Novel Dual GIP and GLP‐1 Receptor Agonist Tirzepatide Attenuates Colon Cancer Development by Regulating Glucose Metabolism

open access: yesAdvanced Science, EarlyView.
Tirzepatide, a dual GIP/GLP‐1 receptor agonist for diabetes, suppresses colorectal cancer growth by targeting glucose metabolism. It inhibits cancer cell proliferation, promotes apoptosis, and induces tumor regression. It reduces glucose uptake and destabilizes HIF‐1α for degradation to downregulate PFKFB3/PFK‐1 enzymes, thus contributing to the ...
Yikai Zhang   +11 more
wiley   +1 more source

Speed vs completeness: a comparative study of solitary and colonial tunicate embryogenesis. [PDF]

open access: yesFront Cell Dev Biol
Anselmi C   +6 more
europepmc   +1 more source

AI-based approach to dissect the variability of mouse stem cell-derived embryo models. [PDF]

open access: yesNat Commun
Caldarelli P   +6 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy