Results 161 to 170 of about 137,065 (307)

The Impact of Melatonin on Cellular Dynamics and Gene Expression of Bovine Embryos Cultured Under Low and High Oxygen Tension. [PDF]

Mol Reprod Dev
Oliveira IRDS, Martins CF, Rodrigues FL, Mello VC, Rodrigues MTO, Faria LC, Amaral HBS, Andrade RV, Fonseca MJP, Dode MAN, Báo SN.   +10 more
europepmc   +1 more source

Technique For Liquid Culture Of Early Chick Embryos Suitable For Long Term Live Imaging

, 2015
This protocol describes the culture of early stage chick embryos in liquid culture with the epiblast side up. We have designed a special culture chamber, in which the embryo is supported by a small layer of heavy silicone oil, effectively sealing of the basal side of the epiblast and forming hypoblast from the surrounding medium. Under these conditions
openaire   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Microfluidics for in vitro fertilization: from science to clinical validation. [PDF]

Hum Reprod Update
Pensabene V, Agate F, Santos Miranda A, Picton HM.   +3 more
europepmc   +1 more source

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

Advanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann, Martijn Dijkstra, Philipp Salomon, Jamie Cowles, Anja Federa, Dina Baier, Carola Jaunecker, Iemima Semerean, Venla Karvonen, Christine Pirker, Maria Sibilia, Dietmar Herndler‐Brandstetter, Petra Heffeter, Bernhard K. Keppler, Christian R. Kowol, Walter Berger   +15 more
wiley   +1 more source

Fluid biopsies for <i>in vitro</i> fertilization: Non-invasive innovations (Review). [PDF]

Med Int (Lond)
Aslan Öztürk S, Kiliç NÖ, Kütük D, Öner Ç.   +3 more
europepmc   +1 more source

Sulfakinin Signaling Sense Circulating Fructose and Suppresses Food Consumption via Insulin‐Like Peptide in Bactrocera Dorsalis

Advanced Science, EarlyView.
This study discovered a new pathway that tells fruit flies when to stop eating. It found that rising blood sugar (fructose) is detected by a sensor called GR43a. This triggers a chain reaction involving the satiety signal sulfakinin and its receptor, ultimately activating a final satiety signal, ILP5.
Hong‐Fei Li, Bao Dong, Zheng‐Lin Ren, Xue‐Guang Zhu, Quan Lei, Yoonseong Park, Jin‐Jun Wang, Hong‐Bo Jiang   +7 more
wiley   +1 more source

Nanoparticle-Based Approaches for Enhancing In Vitro Fertilization in Animal Reproduction. [PDF]

Int J Mol Sci
Gałęska E, Kowalczyk A, Samardžija M, Gregurić Gračner G, Wrzecińska M, Araujo JP, Malagón JÁH, Camiña M, Czerniawska-Piątkowska E, Dobrzański Z.   +9 more
europepmc   +1 more source

Influence of post-thaw embryo culture interval on assisted reproduction techniques pregnancy rates [PDF]

Fertility and Sterility, 2019
Laudislena Colodetti, Patricia Pinho de França, Marcos Sampaio, Selmo Geber   +3 more
openaire   +1 more source

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source