Results 71 to 80 of about 259,561 (269)

Birth of India’s first cloned cattle and analysis of its health and reproduction status: A case study

Scientific Reports
Somatic cell nuclear transfer (SCNT) allows the multiplication of elite livestock and conservation of endangered species. However, restrictions on cow slaughter limit the access to oocytes for SCNT applications in Indian cattle breeds.
Naresh L. Selokar, Manoj K. Singh, Gaurav Tripathi, Kartikey Patel, Ranjeet Verma, Priyanka Singh, Ajay Aswal, Manmohan Singh Chauhan   +7 more
doaj   +1 more source

Bisphenol P induces ovarian dysfunction by directly targeting PTGS2 and disrupting steroid hormone synthesis

Ecotoxicology and Environmental Safety
Emerging evidence suggests structural analogues of bisphenol A (BPA), including the increasingly used substitute bisphenol P (BPP), pose substantial reproductive risks. However, BPP's ovarian toxicity remains uncharacterized.
Dingmei Qin, Zijian Ma, Zhipeng Lin, Lei Wang, Jian Wang, Xing Zhang, Xiaoqing Wu, Jingya Li, Shujun Sun, Shangrong Zhang   +9 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Embryo development in dairy cattle

Theriogenology, 2016
During the past 50 years, the fertility of high-producing lactating dairy cows has decreased, associated with intensive selection for increased milk production. The physiological and metabolic changes associated with high milk production, including decreased (glucose, insulin, IGF-I) or increased (nonesterified fatty acids, ketone bodies ...
Pat Lonergan, Trudee Fair, Niamh Forde, Dimitrios Rizos   +3 more
openaire   +4 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

YOLOv8-BaitScan: A Lightweight and Robust Framework for Accurate Bait Detection and Counting in Aquaculture

Fishes
Excessive bait wastage is a major issue in aquaculture, leading to higher farming costs, economic losses, and water pollution caused by bacterial growth from unremoved residual bait.
Jian Li, Zehao Zhang, Yanan Wei, Tan Wang   +3 more
doaj   +1 more source

A KRABsody for Embryo-Placental Development [PDF]

Developmental Cell, 2017
Many of the hundreds of KRAB zinc finger proteins encoded by human and mouse are involved in taming the transcriptional regulatory potential of transposable elements. Reporting recently in Science, Yang et al. (2017) reveal that one murine family member, ZFP568, controls Igf2 expression for proper embryonic and placental development.
openaire   +3 more sources

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

BPP disrupts spermatogenesis via mitochondrial-ER stress-mediated autophagic flux blockade in mice

Ecotoxicology and Environmental Safety
Endocrine-disrupting chemicals (EDCs), particularly bisphenol A (BPA) and its analogs, have been extensively linked to male reproductive toxicity. However, the biological effects of bisphenol P (BPP), an increasingly used BPA substitute, remain poorly ...
Shangrong Zhang, Dingmei Qin, Zhipeng Lin, Siyu Wang, Lei Wang, Jian Wang, Xing Zhang, Shujun Sun, Qing Ding, Xiangyu Chen, Jingya Li, Jiayu Liu, Zijian Ma, Xiaoqing Wu, Yong Liu   +14 more
doaj   +1 more source