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Paternal factors contributing to embryo quality [PDF]
Journal of Assisted Reproduction and Genetics, 2018 Advancing maternal and paternal age leads to a decrease in fertility, and hence, many infertile couples opt for assisted reproductive technologies [ART] to achieve biological parenthood. One of the key determinants of achieving a live outcome of ART, embryo quality, depends on both the quality of the oocyte and sperm that have created the embryo ...
Stacy, Colaco, Denny, Sakkas
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Медицинский совет, 2021 Introduction. Infertility, i.e. the inability to achieve a clinical pregnancy within 12 months of a regular sexual life without contraception, is a current medical problem and affects up to 15-25% of married couples in Western countries.Objective.
A. G. Syrkasheva, N. V. Dolgushina
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The importance of cytoplasmic strings during early human embryonic development
Frontiers in Cell and Developmental Biology, 2023 Objectives: During human in vitro fertilisation (IVF) treatments, embryologists attempt to select the most viable embryos for embryo transfer (ET). Previously, embryos were evaluated based on light microscopic morphological parameters.
Kata Joo +6 more
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Epigenetics, embryo quality and developmental potential [PDF]
Reproduction, Fertility and Development, 2014 It is very important for embryologists to understand how parental inherited genomes are reprogrammed after fertilisation in order to obtain good-quality embryos that will sustain further development. In mammals, it is now well established that important epigenetic modifications occur after fertilisation.
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Frontiers in Physiology, 2020 ObjectiveThe single-embryo transfer (SET) is the recommended approach to improve the live birth rate and reduce the complications related with multiple pregnancies.
Qianqian Zhu +5 more
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Predicting embryo quality: mRNA expression and the preimplantation embryo
Reproductive BioMedicine Online, 2005 To overcome the low implantation rate (10-20%) following IVF in humans, more than two embryos are commonly replaced, potentially leading to high order multiple pregnancies with associated significantly elevated risks. Selecting the most viable embryos and transferring fewer of them could reduce this risk.
Deirdre, Corcoran +2 more
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Frontiers in Immunology, 2021 BackgroundIt is highly desirable to develop new strategies based on secretomics to more accurately selection of embryos with the highest developmental potential for transfer.
Peilin Chen +11 more
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Diagnostics, 2023 Cell-free DNA fragments detected in blood and in other biological fluids are released from apoptotic/necrotic cells. In this study, we analyzed cfDNA levels in follicular fluid (FF) samples from patients with infertility.
Maria Manuel Casteleiro Alves +6 more
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Association between Number of Formed Embryos, Embryo Morphology and Clinical Pregnancy Rate after Intracytoplasmic Sperm Injection [PDF]
Revista Brasileira de Ginecologia e Obstetrícia, 2016 Introduction Infertility has a high prevalence in the general population, affecting 5 to 15% of couples in reproductive age. The assisted reproduction techniques ( ART ) include in vitro manipulation of gametes and embryos and are an important treatment
Caroline Mantovani da Luz +5 more
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Fertilization signatures as biomarkers of embryo quality
Human Reproduction, 2022 Abstract Fertilization underpins the vital transition from gametic meiosis to embryonic mitosis. For decades, in human IVF, microscopic observation at a single time point has limited our appreciation of the morphokinetic complexity of this process. More recently, the introduction of time lapse technology—also enhanced by combination with
Giovanni Coticchio +4 more
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