Results 41 to 50 of about 284,770 (295)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The transcriptome analysis reveals the regulatory mechanisms of female sterility in Lagerstroemia speciosa ‘Zichan’

open access: yesBMC Plant Biology
Background Ovule abortion presents a major biological obstacle to hybrid breeding in the genus Lagerstroemia, but its molecular regulatory mechanisms remain inadequately understood.
Ruoyong Yin   +6 more
doaj   +1 more source

Predictive value of ultrasound-related scoring system on embryo development in early pregnancy after IVF/ICSI: An observation of embryonic quality

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2019
Objective: This study aims to evaluate the value of the ultrasound-related scoring system on pregnant patients receiving assisted reproductive technology (IVF/ICSI) and early pregnancy outcome.
Xin-Hua Wang   +6 more
doaj   +1 more source

Embryo sac studies in three Indian species of Polypleur(Podostemaceae)

open access: yes, 1977
New combinations for three species of Polypleurum have been proposed. The Apinagia type of embryo sac is recorded for the first time in a species of Polypleurum, P. filifolium. The Dicraea type of embryo sac found in P. dichotomum and P.
Nagendran, C. R.   +2 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Callose and osmiophilic material deposition into walls of developing megagametophyte in Stellaria

open access: yesActa Societatis Botanicorum Poloniae, 2014
Extensive rough ER cisternae are developing and disappearing during each of intermitotic periods in two and four nucleate embryo sac and synergids. The synergid cisternae are transformed into vesicles.
Bohdan Rodkiewicz   +2 more
doaj   +1 more source

The Embryo Sac of Bellis [PDF]

open access: yesBotanical Gazette, 1914
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +2 more sources

Longitudinal paraffin section images of embryo sac.

open access: yes, 2014
Arrow in image D shows the abnormal egg cell in embryo sac, arrow in images B, C, and E shows the normal egg cell in embryo sac. Bar in image A is 50 µm, and images B, C, D, and E have the same magnification as image A.
Ming Li (91180)   +3 more
core   +1 more source

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