In planta analysis of the mode of action of cinmethylin and confirmation of fatty acyl‐ACP thioesterases (FATs) as primary site of action. Cinmethylin inhibits FATs, disrupting eukaryotic de novo lipid biosynthesis and causing defects in cell division, elongation and integrity. We confirm FATs as the primary site of action in planta.
Maximillian Pollmeier +15 more
wiley +1 more source
Human stem cell-based embryo models: from self-organization to recapitulating development. [PDF]
Liu D, He T.
europepmc +1 more source
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan +8 more
wiley +1 more source
First Record of Triplet Embryos in Sea Turtles: Evidence of Natural Polyembryony in a Wild Green Turtle (<i>Chelonia mydas</i>) Nest From Guanahacabibes, Cuba. [PDF]
Azanza-Ricardo J +9 more
europepmc +1 more source
Ground‐based robotic remote sensing for standardized biodiversity monitoring in coastal habitats
Illustrated workflow of the proposed citizen‐to‐robot monitoring pipeline: (i) expert‐validated citizen observations are translated into AI models, (ii) deployed on a ground‐based robotic platform for proximal sensing of coastal dune habitats, (iii) enabling standardized detection of ecological targets (e.g., Pancratium maritimum & Brithys crini), and (
Giovanni Di Lorenzo +5 more
wiley +1 more source
A yolk sac-derived hepatic γδ T cell subpopulation develops in a hematopoietic stem cell- and thymus-independent manner. [PDF]
Chen Y +5 more
europepmc +1 more source
ABSTRACT The current study aimed to quantify the antimicrobials amoxicillin (AMX), cefazolin (CFZ), chloramphenicol (CHL), metronidazole (MTZ), and sulfamethoxazole (SX) in effluents and surface water of an important Cerrado river, calculate their half‐lives, and analyze their ecotoxicity following single and combined exposures.
Náthala Maria Simão +12 more
wiley +1 more source
Establishment of a physiological reference for embryonic development of three SPF duck breeds compared to SPF chickens. [PDF]
Zhang Y +10 more
europepmc +1 more source
ABSTRACT This study evaluated the toxic effects of water‐accommodated fractions (WAFs) of very‐low sulfur fuel oil (VLSFO) on freshwater and marine fish embryos. Embryos of Japanese medaka (Oryzias latipes), Java medaka (Oryzias javanicus), and grass puffer (Takifugu alboplumbeus) were exposed to various concentrations of VLSFO‐WAF, and the effects on ...
Jumpei Matsuo +5 more
wiley +1 more source
Embryonic Torsion and Axial Rotation in Developing Amniotes: Pattern Distribution, Functional Aspects, and Evolutionary Significance. [PDF]
Blackburn DG, Bonneau LJ.
europepmc +1 more source

