Results 91 to 100 of about 165,227 (327)

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Conclusion [PDF]

, 2012
Concluding analysis of the challenges of regulating ...
Elliston, S., McLean, S.
core  

Embryology [PDF]

Human Reproduction, 2012
G. Gandhi, G. Allahbadia, S. Kagalwala, A. Allahbadia, S. Ramesh, K. Patel, R. Hinduja, V. Chipkar, M. Madne, R. Ramani, J. K. Joo, J. E. Jeung, K. R. Go, K. S. Lee, H. Goto, S. Hashimoto, A. Amo, T. Yamochi, H. Iwata, Y. Morimoto, M. Koifman, S. Lahav-Baratz, E. Blais, Z. Megnazi-Wiener, D. Ishai, R. Auslender, M. Dirnfeld, V. Zaletova, E. Zakharova, I. Krivokharchenko, S. Zaletov, L. Zhu, Y. Li, H. Zhang, J. Ai, L. Jin, X. Zhang, N. Rajan, A. Kovacs, C. Foley, J. Flanagan, J. O'Callaghan, J. Waterstone, T. Dineen, E. M. Dahdouh, P. St-Michel, L. Granger, B. Carranza-Mamane, F. Faruqi, T. V. Kattygnarath, F. L. A. F. Gomes, N. Christoforidis, C. Ioakimidou, C. Papas, M. Moisidou, A. Chatziparasidou, M. Klaver, K. Tilleman, P. De Sutter, J. Lammers, T. Freour, C. Splingart, P. Barriere, T. Ikeno, Y. Nakajyo, Y. Sato, K. Hirata, T. Kyoya, K. Kyono, F. B. Campos, M. Meseguer, M. Nogales, E. Martinez, M. Ariza, D. Agudo, L. Rodrigo, J. A. Garcia-Velasco, A. S. Lopes, V. Frederickx, G. Vankerkhoven, A. Serneels, P. Roziers, P. Puttermans, R. Campo, S. Gordts, E. Fragouli, S. Alfarawati, K. Spath, D. Wells, J. Liss, K. Lukaszuk, J. Glowacka, A. Bruszczynska, S. C. Gallego, L. O. Lopez, E. O. Vila, M. G. Garcia, C. L. Canas, A. G. Segovia, A. G. Ponce, R. N. Calonge, P. C. Peregrin, S. Hashimoto, A. Amo, K. Ito, Y. Nakaoka, Y. Morimoto, D. D. Alcoba, E. G. Valerio, M. Conzatti, J. Tornquist, A. P. Kussler, A. M. Pimentel, H. E. Corleta, I. S. Brum, P. Boyer, D. Montjean, P. Tourame, M. Gervoise-Boyer, J. Cohen, B. Lefevre, C. I. Radio, J. P. Wolf, A. Ziyyat, I. De Croo, A. Tolpe, S. Degheselle, A. Van de Velde, K. Tilleman, P. De Sutter, E. Van den Abbeel, S. Kagalwala, G. Gandhi, G. Allahbadia, M. Kuwayama, A. Allahbadia, V. Chipkar, A. Khatoon, R. Ramani, M. Madne, S. Alsule, M. Inaba, A. Ohgaki, A. Ohtani, H. Matsumoto, S. Mizuno, R. Mori, A. Fukuda, Y. Morimoto, Y. Umekawa, A. Yoshida, S. Tanigiwa, K. Seida, H. Suzuki, M. Tanaka, Z. Vahabi, P. E. Yazdi, A. Dalman, B. Ebrahimi, F. Mostafaei, M. R. Niknam, S. Watanabe, M. Kamihata, T. Tanaka, R. Matsunaga, N. Yamanaka, C. Kani, T. Ishikawa, T. Wada, H. Morita, H. Miyamura, E. Nishio, M. Ito, A. Kuwahata, M. Ochi, T. Horiuchi, M. Dal Canto, M. C. Guglielmo, R. Fadini, M. M. Renzini, D. F. Albertini, P. Novara, M. Lain, F. Brambillasca, D. Turchi, M. Sottocornola, G. Coticchio, M. Kato, N. Fukunaga, R. Nagai, H. Kitasaka, T. Yoshimura, F. Tamura, N. Hasegawa, K. Nakayama, M. Takeuchi, H. Ohno, N. Aoyagi, E. Kojima, F. Itoi, V. Puard, A. Sioga   +201 more
openaire   +1 more source

Evolution of the vertebrate skeleton: morphology, embryology, and development

Zoological Letters, 2015
Two major skeletal systems—the endoskeleton and exoskeleton—are recognized in vertebrate evolution. Here, we propose that these two systems are distinguished primarily by their relative positions, not by differences in embryonic histogenesis or cell ...
Tatsuya Hirasawa, S. Kuratani
semanticscholar   +1 more source

The Functional Significance of Cardiac Looping: Comparative Embryology, Anatomy, and Physiology of the Looped Design of Vertebrate Hearts

Journal of Cardiovascular Development and Disease
The flow path of vertebrate hearts has a looped configuration characterized by curved (sigmoid) and twisted (chiral) components. The looped heart design is phylogenetically conserved among vertebrates and is thought to represent a significant determinant
Jörg Männer
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Bostonia. Volume 5 [PDF]

, 1904
Founded in 1900, Bostonia magazine is Boston University's main alumni publication, which covers alumni and student life, as well as university activities, events, and ...
Bowne, Borden P., Fall, George Howard, Geddes, James, Lord, Everett W., Sharp, Arthur Page, Sutherland, John P., Warren, William Marshall   +6 more
core   +1 more source

An early chick embryo as learning model for study of embryology

National Journal of Clinical Anatomy, 2018
Background: In medical education, learning happens by variety of perceptions. In basic science Anatomy, visualization of real structures gives rich learning experience. This type seems deficient in human embryology, that too in the early phases.
Harsh P Mishrikoti, Umesh K Kulkarni
doaj   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source