Results 91 to 100 of about 145,048 (308)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Discourses on pregnancy in Old Javanese Śaiva texts from the perspective of Kawi culture

open access: yesWacana: Journal of the Humanities of Indonesia
This article examines the discourse on pregnancy in the context of Kawi culture. The sources of data discussed here include texts of Śaiva persuasion across various genres and geographical areas, such as the Old Javanese Bhīṣmaprava from the Merapi ...
Putu Eka Guna Yasa   +2 more
doaj   +1 more source

Conclusion [PDF]

open access: yes, 2012
Concluding analysis of the challenges of regulating ...
Elliston, S., McLean, S.
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Imaging far and wide

open access: yeseLife, 2016
A custom-built objective lens called the Mesolens allows relatively large biological specimens to be imaged with cellular resolution.
Raghav K Chhetri, Philipp J Keller
doaj   +1 more source

Die »Notwendigkeit eines Vaters für das Kind« und der Zugang lesbischer Frauen zur Reproduktionsmedizin (The child’s need for a father and access to assisted reproductive technologies by lesbians) [PDF]

open access: yes, 2010
This chapter provides an overview of two broad areas relating to lesbians’ use of reproductive services for family building. First, it identifies strategies used in the building of ‘planned’ lesbian families – where a lesbian couple, the genetic mother ...
Blyth, Eric
core  

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

The Pathogenesis of Ventral Idiopathic Herniation of the Spinal Cord: A Hypothesis Based on the Review of the Literature

open access: yesFrontiers in Neurology, 2017
Idiopathic ventral herniation of the spinal cord (SC) is not often encountered in daily practice. Its clinical prevalence, however, will increase through increasing awareness and more frequent use of MRI.
Ronald H. M. A. Bartels   +4 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

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