Results 61 to 70 of about 145,048 (308)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Eggcellent Adventures in Classroom Embryology: An Intracurricular Guide to Chicken Embryology
In most cases, when a teacher signs up to teach chicken embryology in the classroom, the teacher sets up the incubator and the teacher and class wait for the eggs to hatch. That is the experience.
Shaina Spann, Judy Levings
doaj +3 more sources
Aplasia of the vagina and uterus (Mayer-Rokitansky-Kustner-Hauser syndrome): etiology, pathogenetic aspects and theory of the formation of defect (literature review) [PDF]
The article provides data on the etiology and pathogenesis of genital malformation - vaginal and uterine aplasia (Mayer-Rokitansky-Kustner-Hauser syndrome) at the present stage.
D A Kruglyak +4 more
doaj
Two means two, but must does not mean must:an analysis of recent decisions on the conditions for parental orders in surrogacy [PDF]
This article examines the High Court decisions in Re Z (A Child) (Surrogate Father: Parental Order) [2017] 1 FLR 472 and Re X (A Child) (Parental Order: Time Limit) [2015] 1 FLR 349, which concerned two of the conditions for the granting of ‘parental ...
Brown, Alan
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Ectopic thyroid tissue in the breast: A case report
Ectopic thyroid tissue is a rare condition manifested as the appearance of thyroid tissue outside the thyroid gland. Here, we report a case of ectopic thyroid tissue in the breast. A 48-year-old Chinese woman who was diagnosed with breast cancer received
Gong Zheng, Yang Yan, Liu Zegang
doaj +1 more source
A brief description of the basic patterns of mammalian development of the eye is presented based on events as they occur in human beings. The emphasis is not on the details of this development, but rather on its organization and timing, with a figure of comparative development providing a comparison of similar events in man, rat, mouse, and chick.
openaire +3 more sources
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source

