Vesicular Glutamate Release Is Necessary for Neural Tube Formation. [PDF]
J NeurosciGoyal R +9 more
europepmc +1 more source
Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy
Advanced Science, EarlyView.A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann +15 more
wiley +1 more source
A single cluster of RNA Polymerase II molecules is stably associated with active genes. [PDF]
Nat CommunMukherjee A +8 more
europepmc +1 more source
m<sup>6</sup>A reader Ythdf proteins control retrotransposon B2 repeat expression and safeguard early embryo development. [PDF]
EMBO JSu R +16 more
europepmc +1 more source
A non-transcriptional mitotic function of POU/Oct factors ensures spindle assembly and chromosome segregation. [PDF]
J Cell SciGohel P +4 more
europepmc +1 more source
Development and validation of a predictive model for early blastocyst formation on day 4 post-fertilization. [PDF]
Front Endocrinol (Lausanne)Geng Y +6 more
europepmc +1 more source
Gypenosides mitigate acrylamide-induced oxidative stress, inflammation and lipid metabolic dysregulation in retinal pigment epithelial cells and in zebrafish embryos. [PDF]
Mol Biol RepTchiveleketea GM +5 more
europepmc +1 more source
Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension in <i>Xenopus</i>. [PDF]
ElifeSeo HS +11 more
europepmc +1 more source