Results 21 to 30 of about 895,458 (301)

Amount of Cas9 protein introduced into mouse embryos via electroporation affects the genome-editing rate

The Journal of Reproduction and Development, 2022
Genetically engineered animals can be produced quickly using genome editing technology. A new electroporation technique, technique for animal knockout system by electroporation (TAKE), aids in the production of genome-edited animals by introducing ...
Yui WAKE, Christopher A. VAKULSKAS, Steve E. GLENN, Takehito KANEKO   +3 more
doaj   +1 more source

Exploration of Maternal and Fetal Toxicity Risks for Metronidazole-Related Teratogenicity and Hepatotoxicity through an Assessment in Albino Rats

Toxics, 2023
Metronidazole is the primary antimicrobial drug for treating acute and chronic vaginal pathogens during pregnancy; however, there has been insufficient research on placental disorders, early pregnancy loss, and preterm birth. Here, the potential activity
Mervat A. AbdRabou, Barakat M. Alrashdi, Hadeel K. Alruwaili, Reda H. Elmazoudy, Maha A. Alwaili, Sarah I. Othman, Fawzyah A. Alghamdi, Gehan H. Fahmy   +7 more
doaj   +1 more source

Hepes na produção de embriões bovinos in vitro Hepes on in vitro production of bovine embryos

Ciência Rural, 2000
O objetivo do presente estudo foi de avaliar a amplitude da variação de pH em meios de maturação e de cultivo embrionário, com diferentes concentrações do tampão HEPES.
Marcelo Marcos Montagner, Paulo Bayard Dias Gonçalves, Jairo Pereira Neves, Luís Fabiano Santos da Costa, Ederson Bisognin Bortolotto, Alexandre Morales Farias, Patrícia Stranieri   +6 more
doaj   +1 more source

Endometrial stromal cells of women with recurrent miscarriage fail to discriminate between high- and low-quality human embryos [PDF]

, 2012
Background The aetiology of recurrent miscarriage (RM) remains largely unexplained. Women with RM have a shorter time to pregnancy interval than normally fertile women, which may be due to more frequent implantation of non-viable embryos.
Weimar, Charlotte H. E., Gellersen, Birgit, Heijnen Cobi J., Johanna M T de Vreeden-Elbertse, Jan J. Brosens (109247), de Vreeden-Elbertse Johanna M. T., de Vreeden-Elbertse, Johanna M.T., Nick S Macklon, Macklon Nick S., Kavelaars, Annemieke, Charlotte H. E. Weimar (148304), Nick S. Macklon (148320), Jan J Brosens, Weimar Charlotte H. E., Gellersen Birgit, Cobi J. Heijnen (148314), Brosens Jan J., Macklon, Nick S., Weimar, Charlotte H.E., Kavelaars Annemieke, Cobi J Heijnen, Charlotte H E Weimar, Birgit Gellersen (148307), de Vreeden-Elbertse, Johanna M. T., Brosens, Jan J., Heijnen, Cobi J., Annemieke Kavelaars, Annemieke Kavelaars (12570), Birgit Gellersen, Johanna M. T. de Vreeden-Elbertse (148309)   +29 more
core   +2 more sources

Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos

Science, 2019
Spotting off-targets from gene editing Unintended genomic modifications limit the potential therapeutic use of gene-editing tools. Available methods to find off-targets generally do not work in vivo or detect single-nucleotide changes.
Erwei Zuo, Yidi Sun, Wu Wei, Tanglong Yuan, Wenqin Ying, Hao Sun, Liyun Yuan, L. Steinmetz, Yixue Li, Hui Yang   +9 more
semanticscholar   +1 more source

Culture and storage of pig embryos.

Journal of reproduction and fertility. Supplement, 2020
Studies have consistently demonstrated that 4-cell pig embryos can be cultured to the blastocyst stage in a simple salt solution containing bovine serum albumin (BSA).
Duane L. Davis
semanticscholar   +1 more source

The legal status of in vitro embryos

, 2014
Our science has advanced greatly and continues to do so. While being witnesses to this phenomenon, we are not yet ready to fully accept all of its results which can lead to the improvements of our biological structure, or our lives, in other words. There
S. Samardžić
semanticscholar   +1 more source

Telomere lengths in human oocytes, cleavage stage embryos and blastocysts [PDF]

, 2010
Telomeres are repeated sequences that protect the ends of chromosomes and harbour DNA-repair proteins. Telomeres shorten during each cell division in the absence of telomerase.
J. Rai, Rai, J., S. Turner, Wong, H. P., Hartshorne, Geraldine M., Turner, S., H. P. Wong, G. M. Hartshorne   +7 more
core   +1 more source

Atmospheric pollutants and their impact on murine and human reproduction

Actualidades Biológicas, 2022
Atmospheric pollution is caused by the presence or combination of physical, chemical, or biological pollutants in the air. In recent years, the most studied pollutant is particulate matter (PM), a varied mixture of solid and liquid particles.
Yulieth Guerra-Rangel, Viviana Torres-Osorio   +1 more
doaj   +1 more source

Comparison of two doses of eCG for obtaining embryos in llama [PDF]

SPERMOVA, 2021
The study was developed at the Pampa del Arco Experimental Center of the National University of San Cristóbal de Huamanga, the objective was to evaluate doses of 800 IU (T1) and doses of 1000 IU (T2) of eCG to obtain embryos.
Cesar A. Olaguivel, Jaime Ruiz, Pedro Coila   +2 more
doaj   +1 more source