Results 41 to 50 of about 38,106 (211)
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT In the year 2000 the first once daily long‐acting bioengineered insulin analogue (LAIA), insulin glargine (‘glargine’), a true basal insulin (BI), became available for clinical use. This led to the decline in the 50‐year‐old era and prominence of the intermediate‐acting insulins, neutral protamine Hagedorn (NPH) and lente, requiring twice ...
Geremia B. Bolli +9 more
wiley +1 more source
Transductive data-selection algorithms for fine-tuning neural machine translation [PDF]
, 2019 Machine Translation models are trained to translate a variety of documents from one language into another. However, models specifically trained for a particular characteristics of the documents tend to perform better.
Maillette de Buy Wenniger, Gideon +2 more
core +1 more source
Why licensing authorities need to consider the net value of new drugs in assigning review priorities: Addressing the tension between licensing and reimbursement [PDF]
, 2008 Pharmaceutical regulators and healthcare reimbursement authorities operate in different intellectual paradigms and adopt very different decision rules. As a result, drugs that have been licensed are often not available to all patients who could benefit ...
Angell +6 more
core +1 more source
ESG Thematic Bonds in Emerging Markets: Risk, Uncertainty, and Ambiguity
European Financial Management, EarlyView.ABSTRACT We examine the impact of risk aversion, ambiguity, and uncertainty (geopolitical and economic) on the ESG thematic bond markets in emerging countries. We analyze ESG sovereign (both USD and local currency denominated) and corporate bond markets on the aggregate and regional levels.
Nebojsa Dimic +3 more
wiley +1 more source
Abnormal annealing-induced strengthening in Ni39.3Al15.7Fe45 eutectic medium entropy alloy
Journal of Materials Research and Technology, 2023 Cold-working combined with annealing is frequently used to enhance strength of traditional alloy materials. However, this thermal-mechanical processing is not adapted to the preparation for some near net shape parts.
Yu Wang +6 more
doaj +1 more source
Fair Labor Association 2007 Annual Report [PDF]
, 2007 Assesses the progress made by companies in the move towards sustainable corporate responsibility in their labor standards.
Cheadle, Halton, van Heerden, Auret
core +1 more source
Ibis, EarlyView.Detailed knowledge about bird migration patterns can enhance our understanding of the evolution of migration and temporal changes in space use throughout the annual cycle. Additionally, as many migratory bird species are experiencing population declines, understanding the connectivity between their spatial distributions during breeding, migration and ...
Yosef Kiat +3 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1522-1536, June 2026.Traditionally, clinical outcomes measuring how a patient feels, functions, or survives are preferred endpoints in clinical trials; however, some may take a long time to manifest in slowly developing diseases. Biomarkers, if properly validated, can serve as surrogate endpoints, acting as substitutes for clinical outcomes.
Renske Johanna Grupstra +4 more
wiley +1 more source
The Future of Generic Biologics: Should the United States “Follow-On” the European Pathway? [PDF]
, 2008 The United States is embarking on a biotechnology drug revolution. In the last few decades, biotech drugs have saved millions of lives, and the market for these miracle cures continues to grow at an astronomical rate.
Kaldre, Ingrid
core +1 more source
Systems Engineering, Volume 29, Issue 3, Page 387-405, May 2026.ABSTRACT Structural Complexity is perceived as driving cost in system development, yet managing it effectively requires empirical understanding. This study investigates human decision‐making using a toy transportation‐style network design task, focusing on how Structural Complexity, Effort, and Performance interact. Seventy‐four participants (primarily
Alfonso Lanza +3 more
wiley +1 more source