Results 41 to 50 of about 542,322 (319)

Emerging Options for Emergency Contraception [PDF]

Clinical Medicine Insights: Reproductive Health, 2013
Emergency post-coital contraception (EC) is an effective method of preventing pregnancy when used appropriately. EC has been available since the 1970s, and its availability and use have become widespread. Options for EC are broad and include the copper intrauterine device (IUD) and emergency contraceptive pills such as levonorgestrel, ulipristal ...
Atsuko Koyama, Laura Hagopian, Judith Linden   +2 more
openaire   +4 more sources

Dental Emergencies Management in COVID-19 Pandemic Peak: A Cohort Study [PDF]

, 2021
Julien Beauquis, A.E. Petit, V. Michaux, V. Sagué, Séverine Henrard, Julian Leprince   +5 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

СONSTRUCTION AND THE ALGORITHM OPERATION OF THE LASER COMBINED FIRE DETECTOR

Приборы и методы измерений, 2017
The point optical smoke detector is currently the most effective means of fire detection at the early stage of its occurrence. The urgent task for this type of detector is to increase its sensitivity to «black» smoke and ensure resilience to the effects ...
A. I. Kitsak, A. P. Lushchyk, D. L. Esipovich, V. N. Konon, I. V. Kavalchyk, O. A. Protasevich, I. B. Tretyak   +6 more
doaj   +1 more source

Policy implementation challenges and the ritualization of public health emergency plans: An investigation of urban communities in Jiangsu Province, China

Frontiers in Public Health, 2023
IntroductionThe COVID-19 pandemic has been a global public health emergency, and countries worldwide have responded to it through a vast array of pre-planned, adaptively devised and ad-hoc measures.
Rui Zhang, Chengli Wang, Changgui Li, Yachao Xiong   +3 more
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

‘A tale of two paradoxes in response to COVID-19’: Public health system and socio-economic implications of the pandemic in South Africa and Zimbabwe.

Cogent Social Sciences, 2021
Africa’s response to the outbreak of infectious diseases has come under scrutiny over the years and the outbreak of COVID-19 has exacerbated the situation.
Bellita Banda Chitsamatanga, Wayne Malinga   +1 more
doaj   +1 more source

EMERGENT RELATIVITY [PDF]

International Journal of Modern Physics A, 2003
A possible resolution of the incompatibility of quantum mechanics and general relativity is that the relativity principle is emergent. I show that the central paradox of black holes also occurs at a liquid-vapor critical surface of a bose condensate but is resolved there by the phenomenon of quantum criticality.
openaire   +3 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source