Results 71 to 80 of about 6,367,482 (315)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Global positioning system alerted volunteer first responders arrive before emergency medical services in more than four out of five emergency calls.

Resuscitation, 2020
AIM To evaluate response rates for volunteer first responders (VFRs) activated by use of a smartphone GPS-tracking system and to compare response times of VFRs with those of emergency medical services (EMS). Furthermore, to evaluate 30-day-survival after
L. Sarkisian, H. Mickley, H. Schakow, O. Gerke, G. Jørgensen, M. Larsen, F. Henriksen   +6 more
semanticscholar   +1 more source

Effect of Machine Learning on Dispatcher Recognition of Out-of-Hospital Cardiac Arrest During Calls to Emergency Medical Services

JAMA Network Open, 2021
Key Points Question Can a machine learning model help medical dispatchers improve recognition of out-of-hospital cardiac arrest? Findings In this randomized clinical trial of 5242 emergency calls, a machine learning model listening to calls could alert ...
S. Blomberg, H. Christensen, F. Lippert, A. Ersbøll, C. Torp-Petersen, M. Sayre, P. Kudenchuk, F. Folke   +7 more
semanticscholar   +1 more source

Emergency response ICT systems [PDF]

, 2014
This audit assessed how Information and Communications Technology systems and processes are used to deliver an emergency service response. Overview Victorians rely on emergency services organisations during emergencies and crisis incidents, and expect ...

core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Registered Nurses' experiences of using a clinical decision support system for triage of emergency calls: A qualitative interview study.

Journal of Advanced Nursing, 2020
OBJECTIVES To describe how Registered Nurses make use of a Clinical Decision Support System to triage calls to emergency medical dispatch centres, from the perspective of professional autonomy.
I. Holmström, E. Kaminsky, Ylva Lindberg, Douglas Spangler, U. Winblad   +4 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Caller resistance to perform cardio-pulmonary resuscitation in emergency calls for cardiac arrest.

Social Science & Medicine (1967), 2020
A key objective of an emergency call for cardiac arrest is to recruit a bystander to perform cardio-pulmonary resuscitation (CPR) until the ambulance arrives.
M. Riou, S. Ball, A. Whiteside, S. Gallant, A. Morgan, P. Bailey, J. Finn   +6 more
semanticscholar   +1 more source

A comparison of two emergency medical dispatch protocols with respect to accuracy [PDF]

, 2017
Background: Emergency medical dispatching should be as accurate as possible in order to ensure patient safety and optimize the use of ambulance resources.
Torlen, Klara, Olanders, Knut, Torlén, Klara,, Olanders, K, Castren, Maaret, Bohm, K,, Kurland, Lisa,, Castrén, Maaret,, Lisa Kurland, Kurland, L, Kurland, Lisa, Torlen, K, Castren, M, Katarina Bohm, Knut Olanders, Olanders, Knut,, Bohm, Katarina, Maaret Castrén, Klara Torlén, Bohm, Katarina,, Lund University.   +20 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source