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Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

Advanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan, Shukui Du, Chunfei Li, Xinjie Li, Shuyang Mu, Anran Qu, Hengxu Yan, Chongchong Xu, Jinnong Yang, Jingkai Sun, Yijun Wang, Jiayang Xiao, Fuyuan Zhang, Linlin Wang, Tiegang Li, Rui Zhao, Dawei Guan   +16 more
wiley   +1 more source

Can't Intubate, Can't Oxygenate Airway Failure Due to Post-thyroidectomy Cervical Hematoma: A Case Report. [PDF]

Cureus
Kostares M, Noutsos G, Andritsos E, Stampouloglou P, Piagkou M.   +4 more
europepmc   +1 more source

Factors Influencing Older People's Disaster Preparedness Capacity: A Systematic Review. [PDF]

Int J Older People Nurs
Lee SJ, Hur Y.
europepmc   +1 more source

Optimising local institutional role for sustainable community preparedness in Krinjing: The slope of Merapi Volcano. [PDF]

Jamba
Setyowati DL, Bachri S, Benardi AI, Wijayanto B, Sriyono S, Rahman AU, Wulandari F, Rahmajati JP.   +7 more
europepmc   +1 more source

Radiation cognition, government trust and their potential influencing factors in residents within 30 km of Qinshan nuclear power plant. [PDF]

Front Public Health
Yang S, Hao X, Yuan L, Guo J, Lai Z, Xuan Z, Wang D, Hu G, Yu S, Lei C, Cao Y.   +10 more
europepmc   +1 more source

Emergency and disaster preparedness in the zonal hospitals in the Somali Regional State, Ethiopia: a cross-sectional study. [PDF]

Res Health Serv Reg
Farah B, Pavlova M, Groot W.
europepmc   +1 more source

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Numerical analysis and staircase layout optimisation for a Ro-Ro passenger ship during emergency evacuation

Reliability Engineering and System Safety, 2022
Xinjian Wang, Sean Loughney, Zaili Yang
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BIM-based safety design for emergency evacuation of metro stations

Automation in Construction, 2021
Liz Varga, Nini Xia, Yuchun Tang
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Mapping knowledge structure and research trends of emergency evacuation studies

Safety Science, 2020
Hui Liu, Rui Hong, Hailun Chen
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