Results 201 to 210 of about 516,090 (300)

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

Advanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu   +12 more
wiley   +1 more source

Communication in Emergency General Surgery

, 2023
openaire   +3 more sources

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

Advanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo, Naifeng Zhu, Zhuocheng Lyu, Yifei Liu, Zhenjiang Xu, Chun Zhou, Yaochao Zhao, Changgui Shi   +7 more
wiley   +1 more source

Patient education series: understanding trauma and emergency general surgery conditions. [PDF]

Trauma Surg Acute Care Open
Dilday J, Reilly PM, Haut ER, Martin MJ, Hendershot K.   +4 more
europepmc   +1 more source

Early Outcomes After Total Arch Replacement With Frozen Elephant Trunk in Elderly Patients With Acute Type A Aortic Dissection

AGING MEDICINE, EarlyView.
Across seven centers (2015–2023), we studied 1634 ATAAD patients undergoing TAR+FET and, after propensity matching (n = 699), compared elderly (≥ 60) versus non‐elderly (< 60) outcomes. Elderly patients had higher 30‐day mortality and complications (log‐rank p = 0.002), supporting individualized hybrid strategies, organ‐protective perioperative care ...
Jiajun Liang, Yuan Xue, Yeting Lou, Hao Han, Xiaohan Zhong, Zhou Liu, Tianxu Han, Meili Wang, Wenjian Jiang, Hongjia Zhang, Haiyang Li, Yuanfei Zhao   +11 more
wiley   +1 more source

Evidence-based, cost-effective management of small bowel obstruction: An algorithm of the Journal of Trauma and Acute Care Surgery emergency general surgery algorithms work group. [PDF]

J Trauma Acute Care Surg
Livingston DH, Salim A, Biffl WL, Costantini TW, Diaz JJ, Inaba K, Napolitano LM, Winchell R, Coimbra R.   +8 more
europepmc   +1 more source

Laparoscopic Colorectal Surgery in the Era of Robotics: Evolution, Eclipse, or Equilibrium?

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Minimally invasive colorectal surgery has undergone a remarkable transformation over the past three decades. Laparoscopy, once viewed with skepticism, is now firmly established as a standard approach, supported by robust randomized trials demonstrating oncologic safety and improved recovery compared to open surgery.
Amanjeet Singh, Archit Gupta, Azhar Perwaiz, Adarsh Chaudhary   +3 more
wiley   +1 more source

Barriers faced by surgeons in identifying and managing malnutrition in emergency general surgery: A qualitative study. [PDF]

Colorectal Dis
Ashmore DL, Baker DM, Wilson TR, Halliday V, Lee MJ.   +4 more
europepmc   +1 more source

First Rwanda National Trauma Symposium 2019: Challenges and priorities. [PDF]

, 2020
Bagahirwa, Irene, Benimana, Eric, Bhengu, Busisiwe, Byiringiro, Jean Claude, Dushime, Theophile, Jayaraman, Sudha, Kabagema, Igance, Krebs, Elizabeth, Mbanjumucyo, Gabin, Muhumuza, Arsene, Muneza, Severien, Nahayo, Ernest, Ndayisaba, Gilles, Nkeshimana, Menelas, Ntirenganya, Faustin, Nuhu, Assuman, Nyinawankusi, Jeanne D\u27Arc, Nzeyimana, Innocent, Rosenberg, Ashley, Rutayisire, Lambert, Umwali, Ghislaine, Uwitonze, Costica, Uwitonze, Jean Marie   +22 more
core   +1 more source

First Successful Regeneration of a Structurally Native‐Like Colon Using a Bioabsorbable Polymer Sheet

Annals of Gastroenterological Surgery, EarlyView.
This study demonstrated that a bioabsorbable polymer sheet (BAPS) can regenerate approximately half the circumference of the colon with native‐like structure and function in an experimental setting. As the model involved immediate closure after perforation and did not reproduce peritonitis, caution is required when considering clinical applicability ...
Junpei Takashima, Mitsuo Miyazawa, Masayasu Aikawa, Daisuke Fujimoto, Hirotoshi Kobayashi   +4 more
wiley   +1 more source