Results 41 to 50 of about 1,797,128 (344)

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Emergency management: exposure keratopathy

Community Eye Health Journal, 2018
Exposure keratopathy can result in destruction of the cornea and blindness if not treated urgently.
Wanjiku Mathenge
doaj  

Evolutionary game and simulation analysis on management synergy in China’s coal emergency coordination

Frontiers in Environmental Science, 2023
Once coal mine accidents occur, a series of chain reactions will bring radiation effects that are difficult to solve in the short term to the normal operation of the economy and society.
Peizhe Shi, Peizhe Shi, Yu Hao, Yu Hao, Yu Hao, Chaolun Sun, LiJun Zhang, LiJun Zhang   +7 more
doaj   +1 more source

Wireless E911 Emergency Communications Fund Iowa Homeland Security and Emergency Management Division of the Iowa Department of Public Defense independent auditor's reports, basic financial statements and supplementary information, June 30, 2010. [PDF]

, 2011
Audit report on the Wireless E911 Emergency Communications Fund of the Iowa Homeland Security and Emergency Management Division of the Iowa Department of Public Defense for the year ended June 30 ...

core  

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Knowledge acquisition and dissemination for emergency situation [PDF]

, 2005
Emergency situation is highly uncertain, dynamic, time pressure in making decisions and involves multi organizations and multi jurisdiction level.
Ku-Mahamud, Ku Ruhana, Md Norwawi, Norita   +1 more
core  

Pre-hospital management protocols and perceived difficulty in diagnosing acute heart failure [PDF]

, 2020
Aim To illustrate the pre-hospital management arsenals and protocols in different EMS units, and to estimate the perceived difficulty of diagnosing suspected acute heart failure (AHF) compared with other common pre-hospital conditions.
Banaszewski, Marek, Bot, Emilie, Braun, Fracnois, Celutkiene, Jelena, Chouihed, Tahar, Christ, Michael, Claessens, Yann-Erick, Claret, Pierre-Geraud, Collins, Sean P., Cone, David C., Desmettre, Thibaut, Di Somma, Salvatore, Dunne, Robert B., Dupriez, Florence, Dyani, Mohammed, Escalada, Xavier, Ezekowitz, Justin, Freund, Yonathan, Goldstein, Patrick, Goodloe, Jeffrey M., Gregor, Roman, Guss, David, Hachimi Idrissi, Saïd, Han, Lim Swee, Harjola, Pia, Harjola, Veli-Pekka, Harrell, Andrew J., Hazlitt, Melissa, Hong, Rick, Hoppu, Sanna, Iirola, Timo, Knapp, Joshua M., Korgvee, Ago, Kruse, Nanna, Kuisma, Markku, Kurola, Jouni, Lainscak, Mitja, Laribi, Said, Leach, Robert, Lubin, Jeffrey S., Luk, Jeffrey H., Lund, Vesa, MacNeal, James, Makela, Pekka, Mansour, Cherif, Martikainen, Matti, Martin, Javier, Martin-Sanchez, Francisco J., McKinney, Jared, Mercer, Mary P., Metra, Marco, Meyer, Isabelle, Mimoz, Olivier, Miro, Oscar, Moeckel, Martin, Mols, Pierre, Montassier, Emmanuel, Penaloza, Andrea, Portela, Roberto C., Pruett, Kim, Pumputiene, Vanda, Rekosz, Jerzy, Reuter, Paul-Georges, Ricard-Hibon, Agnes, Rognas, Leif, Rosenberg, Paul, Sandberg, Marten, Swanson, Doug, Tarvasmaki, Tuukka, Tazarourte, Karim, Thys, Frederic, Torronen, Kari, Vannuffelen, Marc, Vermylen, Olivier, Weisberg, Stacy N., Weiss, Dale, Wilen, Susanna, Yee, Allen   +77 more
core   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Smartphone sensing platform for emergency management [PDF]

, 2014
The increasingly sophisticated sensors supported by modern smartphones open up novel research opportunities, such as mobile phone sensing. One of the most challenging of these research areas is context-aware and activity recognition.
Dugdale, Julie, Gonzalez, Jose J., Granmo, Ole-Christoffer, Radianti, Jaziar   +3 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source