Results 101 to 110 of about 1,093,871 (308)

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen, Sunghyun Jun, Colleen M. Arrasmith, Charitha C. Anamala, Mitchell D. Thielen, Anapaula Garcia, Volha Liaudanskaya   +6 more
wiley   +1 more source

Relationship between public awareness and expectations of pre-hospital Emergency Medical Services in Tabriz, Iran, in 2020 [PDF]

Archives of Trauma Research
Background: Awareness of Emergency Medical Services (EMS) procedures is important for the general public to receive emergency services in a timely manner. Understanding public expectations is essential for providing therapeutic interventions and managing
Jafar Khani, Neda Gilani, Abbas Dadashzadeh, Azad Rahmani, Faranak Jabbarzadeh Tabrizi, Nima Gharajeh-Alamdari   +5 more
doaj   +1 more source

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

Advanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla García‐Iglesias, Jagoda Litowczenko, Alba Morillas Garcia, Anton Guimerà, Xavi Illa, Rosa Villa, Angel Raya   +12 more
wiley   +1 more source

rust levels of patients in emergency medical technicians, associated factors, and resulting outcomes [PDF]

Preventive Care in Nursing and Midwifery Journal
Background: Trust between patients and Emergency Medical Technicians (EMTs) is crucial for effective pre-hospital nursing care. Objectives: This study aimed to assess the trust levels of patients in emergency medical technicians, associated factors ...
Alireza Rasouli
doaj   +1 more source

Disparity in emergency medical services across Japan [PDF]

, 2015
By using a prospective, nation-wide, population-based out-of-hospital cardiac arrest (OHCA) database (All-Japan Utstein Registry, January 1, 2005 to December 31, 2012), we examined the disparity in emergency medical services across Japan and found ...
Nakajima, Kazunori, Narukawa, Masaki, Sakamoto, Naoki, Sakata, Kazuya, Takimoto, Taro   +4 more
core  

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

A hybrid strategy using an ambulance and a helicopter to convey thrombectomy candidates to definite care: a prospective observational study

BMC Emergency Medicine
Background Mechanical thrombectomy is the treatment of choice for large vessel occlusion strokes done only in comprehensive stroke centres (CSC). We investigated whether the transportation time of thrombectomy candidates from another hospital district ...
Pauli Vuorinen, Piritta Setälä, Jyrki Ollikainen, Sanna Hoppu   +3 more
doaj   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

Magnetically Actuated Drops‐on‐Stilts Microrobots for Transport and Delivery of Hydrophobic Cargo

Advanced Materials Interfaces, EarlyView.
Iron oxide nanoparticles and oil droplets in external magnetic fields form “drops‐on‐stilts” microrobots that transport hydrophobic cargo. Tunable nanoparticle–droplet interactions generate stilt‐like structures. Field rotation enables walking, obstacle navigation, and collective motion.
Oluwafemi Ligan, Hrishabh Singh, Sahil Kulkarni, Hong Huy Tran, James M. Kikkawa, Daeyeon Lee, Ravi Radhakrishnan, Edward Steager, Hyun Koo, Kathleen Stebe   +9 more
wiley   +1 more source

Anti‐Slip Material‐Based Strategies and Approaches

Advanced Materials Technologies, EarlyView.
This review highlights the principle mechanisms of slipping at the microscale, linking contact mechanics with a friction behavior model for surface interfaces. Main strategies to develop anti‐slip properties to the surfaces are discussed alongside standardized testing approaches.
Sogand Abbaspoor‐Zanjani, Carlo Antonini, Teresa Gatti, Mengjiao Wang   +3 more
wiley   +1 more source