Results 51 to 60 of about 6,291,095 (290)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Work-Stress Burnout in Emergency Medical Technicians and the Use of Early Recollections
, 2000 Numerous studies have indicated the high work-stress burnout and attrition rate of emergency medical technicians. Of these studies, none have attempted to use projective techniques to predict work-stress burnout.
Kosinski, Frederick A., Vettor, Susan M.
core +1 more source
Emergency Medical Responder Certification for Law Enforcement [PDF]
, 2023 Law enforcement agencies should require officers to become Emergency Medical Responder (EMR) certified. The public deserves professionalism and training from law enforcement.
Pittinger, David J.
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Health Science Reports, 2021 Background When children suffer acute pain, the ambulance service is often involved to provide initial assessment, treatment, and transport. Several predictors of effective pain management have been identified, including children who are younger (0‐5 ...
Gregory Adam Whitley +3 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Clinical Pediatric Emergency Medicine, 1999 Abstract In recent years there has been considerable change and improvement in pediatric prehospital education. The evolution of ENIS (emergency medical services) for children has paralleled the evolution of EMS hat with a laf of several years.
David Markenson, George L. Foltin
openaire +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Death anxiety in students of medical emergency and emergency technicians of Sabzevar in 1392 [PDF]
, 2018 Introduction: The death anxiety is defined as the fear of your death and othersâ . Being aware of death is inescapable the anxiety beside that leads to different behaviors and the health care workers are exposed to this kind of anxiety more than others.
Hoseinzade, Mahmoud +4 more
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Procedures in emergency medicine: oropharyngeal airway insertion
, 2013 This video is part of a series of videos demonstrating common procedures performed in the Emergency Medicine setting. It was prepared by Cape Town Emergency Medicine's consultants and registrars. This short simulated video demonstrates the technique of
Oosthuizen, Almero +1 more
core +1 more source