Results 51 to 60 of about 108,239 (309)
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Understanding the Workforce Needs of New Jersey's Public Health and Other Disaster Management Employers [PDF]
This report explores the priority workforce needs of New Jersey's public disaster management system. An advisory group of disaster management-related employers from law enforcement and state and local public health systems and educational institutions ...
Aaron Fichtner +2 more
core
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim +3 more
wiley +1 more source
Understanding Occupational and Skill Demand in New Jersey's Health Care Industry [PDF]
The health care industry in New Jersey employs almost 350,000 people. However, state, national, and international shortages of nurses is raising widespread concern in the industry.
Denise Pierson-Balik +6 more
core
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source
Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle +11 more
wiley +1 more source
Emergency Crisis Services for Psychiatric Boarder Patients at Central Vermont Hospital ED [PDF]
Purpose: This project’s aim was to reduce the length of emergency department (ED) stays for psychiatric boarder patients at Central Vermont Medical Center (CVMC) and prevent unnecessary psychiatric inpatient admissions through access to psychiatric ...
Burzynski, Ann E
core +1 more source
Patients’ and emergency clinicians’ perceptions of improving pre-hospital pain management: a qualitative study [PDF]
Background: The authors aimed to investigate patients' and practitioners' views and experiences of pre-hospital pain management to inform improvements in care and a patient-centred approach to treatment. Methods: This was a qualitative study involving a
Iqbal, Mohammad +2 more
core +1 more source
Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas +39 more
wiley +1 more source

