Results 41 to 50 of about 2,979,495 (301)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
Studies on Cooperative Emergency Regulation of Over-level Floods of Cascade Reservoirs
MATEC Web of Conferences, 2018 Affected by global climate change, the frequency of extreme weather events increases in China, and the suddenness, harmfulness and unpredictability of the flood disaster exceeding the designed level are more serious.
Hua Yue, Ma Guangwen, Yang Gengxin
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Effects of Emergency Regulation of Three Gorges Reservoir During Emergency Response to Tuanzhou Polder Breach [PDF]
长江科学院院报[Objective] This study aims to quantitatively evaluate the effects of the emergency regulation of the Three Gorges Reservoir in response to the Tuanzhou polder breach emergency, thereby improving the understanding of flood control regulation of the Three
ZHOU Jian-yin, GONG Ping, HU De-chao, CUI Zhan-feng
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Glycolysis: an emerging regulator of osteoarthritis
Frontiers in ImmunologyOsteoarthritis (OA) has been a leading cause of disability in the elderly and there remains a lack of effective therapeutic approaches as the mechanisms of pathogenesis and progression have yet to be elucidated. As OA progresses, cellular metabolic profiles and energy production are altered, and emerging metabolic reprogramming highlights the ...
Dingming Jiang +6 more
openaire +3 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
An Emerging Model of Auxin Transport Regulation [PDF]
The Plant Cell, 2002 The hormone auxin plays a critical role in the regulation of plant growth and development. Auxin is transported from cell to cell with strict directionality by uptake and efflux carrier proteins (reviewed by [Muday and DeLong, 2001][1]).
Gloria K, Muday, Angus S, Murphy
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Emerging role of miRNAs in the regulation of ferroptosis
Frontiers in Molecular Biosciences, 2023 Ferroptosis is a kind of cell death which has distinctive features differentiating it from autophagy, necrosis and apoptosis. This iron-dependent form of cell death is described by an increase in lipid reactive oxygen species, shrinkage of mitochondria and decrease in mitochondrial cristae.
Reza Mahmoudi-Lamouki +3 more
openaire +3 more sources
SystemsAiming at the problems of low information coordination efficiency and insufficient sustained user participation in emergency document systems during incident response, this paper proposes a user stickiness-based loyalty contagion and adaptive regulation ...
Yike Feng, Yan Song
doaj +1 more source