Results 191 to 200 of about 268,036 (302)

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

Advanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla García‐Iglesias, Jagoda Litowczenko, Alba Morillas Garcia, Anton Guimerà, Xavi Illa, Rosa Villa, Angel Raya   +12 more
wiley   +1 more source

Initial Fire Disposal Technology for Electric Wires: Active Fire Prevention and Extinguishing Concepts

ACS Omega
Zhixin Tang, Tianwei Zhang, Hao Liu, Zidong Guo   +3 more
doaj   +1 more source

A Study of the Improved A* Algorithm Incorporating Road Factors for Path Planning in Off-Road Emergency Rescue Scenarios. [PDF]

Sensors (Basel)
Zhao D, Ni L, Zhou K, Lv Z, Qu G, Gao Y, Yuan W, Wu Q, Zhang F, Zhang Q.   +9 more
europepmc   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Experience and training needs of nurses in military hospital on emergency rescue at high altitude: a qualitative meta-synthesis. [PDF]

BMC Nurs
Zhao R, Fang S, Li D, Zhang C.
europepmc   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

Comprehensive risk management of health, safety and environment for social emergency rescue organization. [PDF]

Heliyon
Wang M, Zhang H, Luo Y, Xu M.
europepmc   +1 more source

Evaluation of a Simplified Loops System for Emergency Rescue Lifting of the Stranded or Recumbent Horse. [PDF]

Animals (Basel), 2019
Madigan J, Costa L, Nieves S, Horgan M, Weberg K, Aleman M.   +5 more
europepmc   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Multi-index comprehensive evaluation model for assessing risk to trainees in an emergency rescue training base for building collapse. [PDF]

Sci Rep
Li J, Huang Z, Wang H, Ding H, Jia Q, Zhao W, Le T, Jameel D, Wang P.   +8 more
europepmc   +1 more source