Results 91 to 100 of about 814,717 (310)

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

Advanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen, Hao Shi, Junxian He, Ziyu Liu, Yuanyuan Zhu, Xiaoyan Liang, Guihua Liu, Xing Yang   +7 more
wiley   +1 more source

Understanding the emergency medical service response to patients who are at imminent risk of out-of-hospital cardiac arrest

Paramedicine
Study Aim: To understand the survival and emergency medical service call triage and response to patients who suffer an out-of-hospital cardiac arrest after the emergency medical service call is connected.
Kim Kirby, Paul White, Sarah Voss, Jonathan Benger   +3 more
doaj   +1 more source

Healthcare Utilization Analysis for Housing First Program in Anchorage Alaska [PDF]

, 2015
Presented to the Faculty of the University of Alaska Anchorage In Partial Fulfillment of Requirements For the Degree of MASTER OF PUBLIC HEALTHHomelessness, especially for the chronically homeless individual with substance abuse issues, often results
Becker, Gandy
core  

Emergency Care Handover (ECHO study) across care boundaries : the need for joint decision making and consideration of psychosocial history [PDF]

, 2013
Background: Inadequate handover in emergency care is a threat to patient safety. Handover across care boundaries poses particular problems due to different professional, organisational and cultural backgrounds.
Apker, Arora, Banerjee, Behara, Bomba, Bost, Catchpole, Cheung, Cohen, Haig, Hilligoss, Hodges, Institute of Medicine, Johnson, Laurence Fitton, Mark A Sujan, Matthew Inada-Kim, Matthew W Cooke, Michelle Rudd, O'Leary, Patterson, Peter Chessum, Peter Spurgeon, Petersen, Pope, Pothier, Raduma-Tomas, Solet, Talbot, Ye   +29 more
core   +2 more sources

Cognitive Trajectories from Preclinical Alzheimer's Disease to Dementia

Advanced Science, EarlyView.
A continuous, multi‐domain characterization of cognitive decline across the Alzheimer's disease spectrum identifies when individual cognitive measures become abnormal. Episodic memory declines first, followed by executive function, language, processing speed, and visuospatial abilities, supporting improved clinical interpretation and optimized endpoint
Fredrik Öhman, Lars Lau Raket, Michael Schöll, for the Alzheimer's Disease Neuroimaging Initiative†   +3 more
wiley   +1 more source

NIBAN2/FLII/RREB1 Axis Drives Glioma Stem Cell Malignancy via TLR3 Pathway Activation

Advanced Science, EarlyView.
NIBAN2, highly expressed in glioma stem‐like cells (GSCs), assembles with FLII and transcription factor RREB1 to form a nuclear complex. This complex transcriptionally activates stemness‐associated genes (e.g., CD44, NANOG) and metabolic enzymes (e.g., LDHA), thereby sustaining both transcriptional and metabolic stemness programs.
Liang liang Shi, Xinwei Qiao, Yue Hu, Minjie Wang, Shaojie Yu, Zihan Gong, Yuxin Rao, Hui Zheng, Siting Chen, Lin Li, Rong Fu, Tao Liang, Jin Yao, Xiaobing Jiang, Junjun Li   +14 more
wiley   +1 more source

Phenotypic Diversity and Outcomes in Pediatric NMDA Receptor Encephalitis: A 15‐Year Retrospective Study from the Largest Children's Hospital in the United States

Advanced Science, EarlyView.
ABSTRACT Anti‐NMDAR encephalitis (NMDARE) is an autoantibody‐mediated disorder characterized by seizures, movement disorders, neurocognitive deficits, and psychosis, but the complete phenotypic heterogeneity, and outcomes are incompletely understood in children.
Alexander J. Sandweiss, Timothy Erickson, Yike Jiang, Varun Kannan, Jonathan M. Yarimi, Kristen S. Fisher, Nikita Shukla, Tim Lotze, Eyal Muscal, Kristy O. Murray   +9 more
wiley   +1 more source

The Role of Emergency Medicine Specialist on Performance of the Emergency Department of Kerman Shahid Bahonar Hospital: A Qualitative Study [PDF]

, 2016
The Role of Emergency Medicine Specialist on Performance of the Emergency Department of Kerman Shahid Bahonar Hospital: A Qualitative Study Ghorbani Nia Rahil1*, Amiresmaeili MohammadReza2, NekoeiMoghadam Mahamod3, Saberi Nia Amin4 1.
Amiresmaeili, MohammadReza, Ghorbani Nia, Rahil, NekoeiMoghadam, Mahamod, Saberi Nia, Amin   +3 more
core  

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

Advanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza, Simone Capuani, Melissa A. Willman, Alexander Rabassa, Ashley L. Joubert, Tommaso Bo, Letizia Franco, Marzia Conte, Ana L. Anaya‐García, Gabrielle E. Rome, Rim Ouni, Henry J. Seaborne, Camden A. Caffey, Dora M. Berman, Junjun Zheng, Jesus Paez‐Mayorga, Corrine Ying Xuan Chua, Shu Hsia Chen, Norma S. Kenyon, Alessandro Grattoni   +19 more
wiley   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source