Results 171 to 180 of about 409,908 (313)

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

open access: yesAdvanced Science, EarlyView.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang   +13 more
wiley   +1 more source

Detecting Pediatric Emergency Service Use for Suicide and Self-Harm: Multimodal Analysis of 3828 Encounters. [PDF]

open access: yesJMIR Ment Health
Edgcomb JB   +7 more
europepmc   +1 more source

Injectable Hydrogel with Rapid Coagulation, Low Swelling, and High Burst Pressure Tolerance Properties for Long‐Term Management of Bleeding Wound

open access: yesAdvanced Science, EarlyView.
An injectable PACmC hydrogel with “rigid island‐flexible chain” architecture is developed, featuring low swelling (49.2% within 7 d), strong wet adhesion (46.5 kPa), and high burst pressure (701 mm Hg), which can achieve rapid hemostasis and long‐term sealing in rabbit and porcine models of hepatic and splenic hemorrhage.
Yang Ouyang   +12 more
wiley   +1 more source

An assessment of information needs and workflows for emergency service providers and caregivers of children with medical complexity. [PDF]

open access: yesBMC Health Serv Res, 2023
Honcoop A   +7 more
europepmc   +1 more source

Selective Interfacial Barriers Drive High‐Performance GeTe Thermoelectrics

open access: yesAdvanced Science, EarlyView.
Carrier‐phonon decoupling is the key to developing high‐performance thermoelectric materials. Here, we demonstrate that selective interfacial barriers can decouple carrier and phonon transport, thus achieving an exceptional peak ZT of ∼2.7 at 773 K, along with a record‐high average ZT of 1.9 across 300–773 K in the (Ge0.82Mn0.04Bi0.04Pb0.1Te)0.99(VSe2 ...
Liang‐Cao Yin   +12 more
wiley   +1 more source

COVID-19 pandemic in minor psychiatric disorders among mobile emergency service workers: cohort. [PDF]

open access: yesRev Bras Enferm
Guedes NDSI   +5 more
europepmc   +1 more source

Phase‐Resolved Defect Transport Mechanisms Governing Asynchronous Ordering in a Eutectic High‐Entropy Alloy

open access: yesAdvanced Science, EarlyView.
Phase‐resolved experiments and atomistic simulations reveal asynchronous ordering behaviors in a eutectic high‐entropy alloy during isothermal annealing. Distinct defect transport mechanisms are identified in coexisting B2 and BCC phases, showing that vacancy and interstitial mediated diffusion governs phase‐dependent thermal stability.
Huiwen Yao   +5 more
wiley   +1 more source

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