By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang +13 more
wiley +1 more source
Detecting Pediatric Emergency Service Use for Suicide and Self-Harm: Multimodal Analysis of 3828 Encounters. [PDF]
Edgcomb JB +7 more
europepmc +1 more source
Prehospital Emergency Service Use for Substance-Related Issues before and during COVID-19. [PDF]
Kabadayi Sahin E, Usul E.
europepmc +1 more source
An injectable PACmC hydrogel with “rigid island‐flexible chain” architecture is developed, featuring low swelling (49.2% within 7 d), strong wet adhesion (46.5 kPa), and high burst pressure (701 mm Hg), which can achieve rapid hemostasis and long‐term sealing in rabbit and porcine models of hepatic and splenic hemorrhage.
Yang Ouyang +12 more
wiley +1 more source
When Agitation Meets Intoxication: A Retrospective Comparison of Intramuscular Olanzapine and Haloperidol Among Patients With and Without Substance Use in a Psychiatric Emergency Service. [PDF]
Lynch ST +6 more
europepmc +1 more source
An assessment of information needs and workflows for emergency service providers and caregivers of children with medical complexity. [PDF]
Honcoop A +7 more
europepmc +1 more source
Selective Interfacial Barriers Drive High‐Performance GeTe Thermoelectrics
Carrier‐phonon decoupling is the key to developing high‐performance thermoelectric materials. Here, we demonstrate that selective interfacial barriers can decouple carrier and phonon transport, thus achieving an exceptional peak ZT of ∼2.7 at 773 K, along with a record‐high average ZT of 1.9 across 300–773 K in the (Ge0.82Mn0.04Bi0.04Pb0.1Te)0.99(VSe2 ...
Liang‐Cao Yin +12 more
wiley +1 more source
COVID-19 pandemic in minor psychiatric disorders among mobile emergency service workers: cohort. [PDF]
Guedes NDSI +5 more
europepmc +1 more source
Effectiveness of ultrasound screening in right upper quadrant pain: A comparative study in a basic emergency service. [PDF]
Miravent S +4 more
europepmc +1 more source
Phase‐resolved experiments and atomistic simulations reveal asynchronous ordering behaviors in a eutectic high‐entropy alloy during isothermal annealing. Distinct defect transport mechanisms are identified in coexisting B2 and BCC phases, showing that vacancy and interstitial mediated diffusion governs phase‐dependent thermal stability.
Huiwen Yao +5 more
wiley +1 more source

