Results 191 to 200 of about 6,068,527 (308)

Disaster Preparedness depends on Disaster Types Expected and the Training, Equipment, and Functioning of Emergency Services. [PDF]

Indian J Crit Care Med
Finsterer J.
europepmc   +1 more source

When the money runs out: why emergency services should be concerned about local authority insolvency

In this webinar, we explore the growing crisis of local authority finance, the impact on the emergency services and ask whether in an election year, local leaders should be pushing this topic to the top of the ...
Murphy, P, Levin, C, Hoddinott, S
core  

Mechanism‐Informed Language Modeling and Oxygenated 3D Screening Identify Berberine–Enzalutamide Synergy in Prostate Cancer Models

Advanced Science, EarlyView.
By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo, Katie Shi, Lina Kafadarian, Alexandra Bermudez, Johnny Diaz, Liam Edwards, Yunqi Hong, Ziyi Chen, Hyeonji Hwang, Weihong Yan, Alan Levinson, Robert Damoiseaux, Cho‐Jui Hsieh, Tanya Stoyanova, Andrew S. Goldstein, Neil Y.C. Lin   +15 more
wiley   +1 more source

Comfort and Person-Centered Care: Adaptation and Validation of the Colcaba-32 Scale in the Context of Emergency Services. [PDF]

Nurs Rep
Marques MDC, Goes M, João A, Oliveira H, Mendes C, Pires R, Bravo N.   +6 more
europepmc   +1 more source

Nuciferine Suppresses Inflammatory Hepatocarcinogenesis by Targeting cPLA2‐Dependent Arachidonic Acid Metabolism

Advanced Science, EarlyView.
Nuciferine directly binds the C2 domain of cPLA2, impairing its Ca2+‐dependent membrane translocation and activation. By suppressing arachidonic acid release and downstream pro‐inflammatory eicosanoid production, nuciferine attenuates NF‐κB signaling and inflammatory hepatocarcinogenesis, revealing cPLA2 as a direct molecular target underlying its ...
Jing Sun, Xinyan Wu, Shuwei Luo, Yilang Liu, Jie Liu, Jun Lu, Weimin Wang, Xiao Feng, Tuo Zhang, Dipak Panigrahy, Jianjun Deng, Xiaojun Liao, Haixia Yang   +12 more
wiley   +1 more source

"It's a last straw situation"; Overdose response and preferences for seeking support from emergency services during overdose in rural Ohio. [PDF]

PLoS One
Colston DC, Go VF, Barrington C, Sibley AL, Piscalko HM, Limarzi-Klyn L, Miller WC.   +6 more
europepmc   +1 more source

NCLX Inhibition plus Ca2+ Delivery Potentiates Electroporation and Antitumor Immunity in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Electroporation combined with NCLX inhibition and Ca2+ delivery induces mitochondrial Ca2+ overload in PDAC cells, triggering pyroptosis, DAMP release, and antitumor immune activation. Simultaneously, suppression of tumor‐derived SPP1 weakens SPP1–CD44 signaling and remodels macrophages toward an antitumor phenotype, thereby enhancing CD8+ T‐cell ...
Chuanbing Zhao, Long He, Yu Lu, Zanglong Deng, Hongzhen Wei, Yunpeng Zhang, Ming Yang, Tao Yin   +7 more
wiley   +1 more source

Climate resilience adaptation and psychiatric emergency services utilization during extreme heat in Boston, MA: a difference-in-differences analysis. [PDF]

Environ Int
Black-Ingersoll F, Willis MD, White JS, Grady ST, Vrkljan KA, Duncan A, Burrows K, Oblath R, Nori-Sarma A.   +8 more
europepmc   +1 more source

CeO2‐Based Electrocatalysts for the Oxygen Evolution Reaction: Design, Dynamic Mechanisms, and Electrolyte Adaptability

Advanced Science, EarlyView.
This Review shows how cerium oxide helps water‐splitting catalysts work better and last longer. It explains how CeO2 tunes electronic structure, oxygen‐vacancy behavior, and surface reconstruction, while adapting to alkaline, acidic, and seawater conditions.
Zhen Cui, Ailing Song, Zirui Cui, Manman Duanmu, Zhipeng Ma, Hao Liu, Guangjie Shao, Xinyi Tan, Guoxiu Wang, Hao Tian   +9 more
wiley   +1 more source

Feasibility and utility of telemedical support through a paramedic-led primary response service to aid emergency services in northwestern Germany. [PDF]

BMC Health Serv Res
Overheu D, Schäfer ST, Rosner B, Warnecke T, Jacobsen N.   +4 more
europepmc   +1 more source