Results 221 to 230 of about 83,244 (304)

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

Brain Pathology, EarlyView.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga, Eva Fernández‐Muñoz, Jorge M. Charco, Enric Vidal, Diego Herrero‐Martínez, Josu Galarza‐Ahumada, Cristina Sampedro‐Torres‐Quevedo, Samanta Giler, Mariví Geijo, Gloria González‐Aseguinolaza, Hasier Eraña, Joaquín Castilla   +11 more
wiley   +1 more source

Assessment of the Risk of Venous Thromboembolism in Overcrowded Shelters: A Geospatial and Statistical Analysis of the 2024 Noto Peninsula Earthquake. [PDF]

Cureus
Nakai H, Horiike R, Itatani T, Tokuoka M, Maeda A, Iida H, Aoki Y, Toda D, Oe M.   +8 more
europepmc   +1 more source

Homo sapiens, industrialisation and the environmental mismatch hypothesis

Biological Reviews, EarlyView.
ABSTRACT For the vast majority of the evolutionary history of Homo sapiens, a range of natural environments defined the parameters within which selection shaped human biology. Although human‐induced alterations to the terrestrial biosphere have been evident for over 10,000 years, the pace and scale of change has accelerated dramatically since the onset
Daniel P. Longman, Colin N. Shaw
wiley   +1 more source

Commentary: Research on the allocation of 3D printing emergency supplies in public health emergencies. [PDF]

Front Public Health
Nair SR, Nagarajan P, Thampi SG, P R.
europepmc   +1 more source

Decision‐Making in Emergency Foster Care: An Insider Perspective on Current Practices and Possibilities for Change

Child &Family Social Work, EarlyView.
ABSTRACT Emergency foster care is a protection measure for children who are in a situation of abuse and/or neglect—or at imminent risk of it—that requires an assessment to make a decision. In Catalonia (Spain), emergency foster care placements are designed for children aged 0–6 and can last up to a maximum of 6 months.
Rosa Sitjes‐Figueras, Carme Montserrat, Pere Soler‐Masó, Joan Llosada‐Gistau   +3 more
wiley   +1 more source

Women's health and rights in conflict: the impact of renewed violence in Lebanon. [PDF]

Sex Reprod Health Matters
El Kak F.
europepmc   +1 more source

A Mixed‐Methods Study on the Associations Between Community Resilience and Parental Self‐Efficacy Among Parents of Children With Autism During War: The Mediating Role of Stress, Anxiety and Depression

Child &Family Social Work, EarlyView.
ABSTRACT Individuals with disabilities, particularly those with autism spectrum disorders (ASD), are highly vulnerable during times of war. This study explored the experiences of Israeli parents of children with ASD during the Swords of Iron War, focusing on community resilience, psychological distress and parental self‐efficacy.
Ayelet Gur, Neora Sarusi, Inbal Bechar Katz, Shlomit Shnitzer‐Meirovich   +3 more
wiley   +1 more source

Building a comprehensive understanding of 2SLGBTQ+ youth homelessness: a scoping review. [PDF]

Int J Equity Health
Abramovich A, Elkington N, Silberberg M, Pang N, Stark R, Bonato S.   +5 more
europepmc   +1 more source

Mothering Through the Experiences of Homelessness With a Particular Focus on Child Separation in High‐Income Countries: A Scoping Review

Child &Family Social Work, EarlyView.
ABSTRACT Mothers who experience homelessness represent one of the most vulnerable and marginalized groups, often facing separation from their children as a consequence of housing instability and intersecting challenges. While there is a substantial body of research on parenting in the context of homelessness, little is known about the experience of ...
Olayinka Ariba, Abe Oudshoorn, Cheryl Forchuk, Nadine Wathen, Corinna Easton, Roxanne Isard   +5 more
wiley   +1 more source

Critical determinants of morbidity and adverse outcomes during the Hajj using the Haddon matrix and the combined model. [PDF]

Sci Rep
Almuzaini Y, Alamri F, Alabdullatif L, Khan A.   +3 more
europepmc   +1 more source