Results 61 to 70 of about 1,736,582 (363)
Frontiers in Energy Research, 2022 The high-pressure tritium leakage is a typical nuclear leakage accident, which can cause radioactive harm. The study aims at the tritium leakage problem in the high-pressure vessel of a nuclear reactor, installing a typical tritium leakage scenario and ...
Changjun Li +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Treatment of Mechanical Corneal Wounds Emergencies during the COVID-19 Pandemic: Absorbable 10-0 Vicryl (Polyglactin 910) Sutures as a Suitable Strategy [PDF]
, 2022 Nicolas Abihaidar +3 more
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Malignant priapism due to penile metastases. Case series and literature review [PDF]
, 2016 Malignant priapism secondary to penile metastases is a rare condition. This term was originally used by Peacock in 1938 to describe a condition of painful induration and erection of the penis due to metastatic infiltration by a neoplasm.
DE DOMINICIS, Carlo +7 more
core +2 more sources
Neuropathic pain: emerging treatments [PDF]
British Journal of Anaesthesia, 2008 Neuropathic pain remains one of the most challenging of all neurological diseases and presents a large unmet need for improved therapies. Many mechanistic details are still lacking, but greater knowledge of overlapping mechanisms and disease comorbidities has highlighted key areas for intervention. These include peripheral and central hyperexcitability.
openaire +2 more sources
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
NH Department of Helath and Human Services Public Health Laboratories Shellfish Program Activites January 2006 – December 2006 [PDF]
, 2007 The Department of Health and Human Services-New Hampshire Public Health Laboratories (DHHS-NHPHL) has continued to carry out various actions providing laboratory analyses for the routine water quality monitoring, “Red Tide” monitoring, and additional ...
Wikoff, Peter C
core +2 more sources
Perforated small intestine in a patient with T-cell lymphoma; a rare cause of peritonitis [PDF]
, 2016 The nontraumatic perforations of the small intestine are pathological entities with particular aspects in respect to diagnosis and treatment. These peculiarities derive from the nonspecific clinical expression of the peritonitis syndrome, and from the ...
Banu, Petrisor +3 more
core +3 more sources
Is tactical algorithmization possible for infectious lesions of the spine? Literature review
Хирургия позвоночника, 2020 Non-specific infectious lesions of the spine present a severe clinical problem due to the high risk of the septic complications and possible mortality.
Mikhail A. Mushkin +3 more
doaj +1 more source