Results 31 to 40 of about 16,565 (265)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Realidad Aumentada del Conocimiento del Medio Ambiente Social en el salón de clases de Primaria

open access: yesRevista Caribeña de Investigación Educativa, 2020
The increased use of information and communication technologies is now a reality that cannot be ignored. The portals, blogs, videos, etc., that we can find on the internet about positive experiences of their use show that the teacher-mediated use of them
Verónica Marín-Díaz   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

THE DIGITAL REALITY FROM THE PERSPECTIVE OF COMMUNICATION PROCESSES AND EXISTENSE OF HUMAN

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2019
Purpose. The article deals with the existence of digital area and term of digital reality in the paradigm of human existential space. It’s analyzing the terminological apparatus from the perspective of modern cybersystems and digital technologies.
Ekaterina Viktorovna Lazinina
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Emerging technologies and applications of wireless communication in healthcare

open access: yesJournal of Communications and Networks, 2011
Future healthcare systems are anticipated to offer high quality services to patients with low costs through a variety of applications enabled by wireless and information technologies. This is because these wireless-equipped healthcare systems can remotely and continuously monitor the patients' health status in both residential settings and outdoor ...
Xuemin (Sherman) Shen   +4 more
openaire   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Humanités numériques responsables

open access: yesTerminal, 2016
Digital Humanities cannot be summarized by enhanced documentation sciences. They reconfigure the knowledge themselves. This article starts from the origins of humanities, to compare and link under different ways the sciences that read and the ones that ...
Bernard Reber
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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