Results 131 to 140 of about 1,764,888 (296)

Characteristics of Emerging Adulthood and Emotion Dysregulation for Predicting Well-Being: Contributions of Qualitative Comparative Analysis

[EN] Emerging adulthood is a developmental stage where individuals may face challenges in emotion regulation and well-being. While there has been progress in well-being research in recent years, studies analyzing the combination of emerging adulthood ...
De-la-Barrera, Usue, Gil-Gómez, José-Antonio, Montoya-Castilla, Inmaculada, Velert-Jiménez, Saray   +3 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Challenges of Emerging Adulthood: the transition to adulthood and the path to autonomy

reservedQuesto elaborato si occupa di approfondire il periodo di passaggio dalla fine dell'adolescenza all'ingresso nel mondo degli adulti, cioè l'Emerging Adulthood, e delle difficoltà che oggi incontrano gli adulti emergenti, ossia i ragazzi dai 18 ...
ROSSI, LUISA
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Identitätsentwicklung und Emerging Adulthood [PDF]

, 2011
Das Ziel der vorliegenden Untersuchung war es herauszufinden, ob sich die emerging adults in Abhängigkeit ihres Identitätstyps in den Merkmalen von Emerging Adulthood, in den notwendigen Kriterien des Erwachsenenalters, in ihrem Explorationsverhalten und
Koenig, Uschi
core  

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Are being responsible, having a stable job, and caring for the family important for adulthood? Examining the importance of different criteria for adulthood in Italian emerging adults

, 2016
In this chapter, we sought to further expand emerging adulthood literature by examining in depth how Italian young people perceive the transition to adulthood and which factors can account for differences in this ...
S. Tagliabue, CROCETTI, ELISABETTA
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