Results 71 to 80 of about 331,057 (285)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Body Image, Self-Esteem, Weight, and Weight Stigma In Male and Female College Students [PDF]

, 2019
Emerging adulthood is a developmental period in which college-aged individuals have greater risk for lower self-esteem and more issues with body image.
Smith, Carlie
core   +2 more sources

Contestable adulthood: variability and disparity in markers for negotiating the transition to adulthood [PDF]

, 2007
Recent research has identified a discreet set of subjective markers that are seen as characterizing the transition to adulthood. The current study challenges this coherence by examining the disparity and variability in young people’s selection of such ...
Adams, G., Arnett, J. J., Arnett, J. J., Arnett, J.J., Ava D. Horowitz, Baker, C.D., Billig, M., Catan, L., Connolly, W.E., Dwyer, P., Dwyer, P., Edwards, D., Furlong, A., Gallie, W.B., Garfinkel, H., Potter, J., Rachel D. Bromnick, Reifman, A., Widdicombe, S.   +18 more
core   +2 more sources

Personality and phobias in adolescence: age and gender in psychopathological expressions [PDF]

, 2019
Background: Although the understanding of adolescent phobias is important, this phenomenon has thus far not been adequately researched. This report, based on clinical experience, highlights prevalent phobic phenomena linked to personality characteristics.
Alibrandi, Angela, Dritto, Irene Pagano, Frisone, Fabio, Merlo, Emanuele Maria, Settineri, Salvatore, Sicari, Federica, Strangis, Fiorella   +6 more
core   +3 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Emerging Adulthood, a Pre-adult Life-History Stage

Frontiers in Endocrinology, 2020
The duration of human maturation has been underestimated; an additional 4–6-year pre-adult period of “emerging adulthood,” should be included in models of human maturation.
Ze′ev Hochberg, Melvin Konner
doaj   +1 more source

Adulthood: the Contemporary Redefinition of a Social Category [PDF]

Social trends such as delayed or forfeited family formation, postponed home leaving and allegedly infantilising leisure practices are often marshalled in support of a long standing social scientific as well as popular assumption: successive generations ...
Harry Blatterer
core