Results 31 to 40 of about 86,118 (307)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Financial Spillovers in Asian Emerging Economies

open access: yesAsian Development Review, 2020
This paper explores financial spillovers between emerging Asia and advanced economies using principal component analysis to extract common shocks in Asia.
Shin-ichi Fukuda, Mariko Tanaka
doaj   +1 more source

Supply shocks and monetary policy responses in emerging economies

open access: yesLatin American Journal of Central Banking, 2022
Supply shocks bring about important dilemmas for monetary policy in emerging economies. We compute monetary policy responses to supply shocks using quarterly data and a Bayesian panel VAR for 24 emerging economies during the period 2004–2019.
José Antonio Ocampo, Jair Ojeda-Joya
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Analysis of the Impact of External Debt on Health in an Emerging Asian Economy: Does FDI Matter?

open access: yesFrontiers in Public Health, 2022
In this study, our main objective is to find the impact of FDI and external debt on health outcomes in emerging Asian economies from 1991 to 2019. To that end, we have collected data for seven economies: Bangladesh, Malaysia, Philippines, Thailand, Sri ...
Yechi Ma, Mengyun Hu, Quratulain Zafar
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Patterns of Frugal Innovation in Healthcare

open access: yesTechnology Innovation Management Review, 2018
Frugal innovations have the potential to offer simple and cost-effective solutions to the healthcare challenges of the world. However, despite the potential for frugal innovations in healthcare, this context has been rarely studied. The objective of this
Hareem Arshad   +2 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Outward foreign direct investment in emerging economies: A case of Turkey [PDF]

open access: yes, 2017
Outward Foreign Direct Investment (OFDI) has been utilized by developed economies to enter developing markets for competitive advantages. However, recent boom in OFDI from emerging economies has prompted the question as to why these economies are ...
Demir, Oğuz, Moiz, Muhammad
core   +1 more source

Restrictive policy impacts in emerging economies

open access: yesCogent Economics & Finance, 2020
The policy responses to capital flows in emerging markets are multiple. However, capital inflow controls, if applied sufficiently broadly, can buttress all other policies by limiting the volume of capital inflows and address balance sheet vulnerabilities.
Chokri Zehri
doaj   +1 more source

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