Results 241 to 250 of about 9,693,931 (354)

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

Arthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K. de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P. Denton, Madelon C. Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source

A unified framework for diagnostic test development and evaluation during outbreaks of emerging infections. [PDF]

Commun Med (Lond)
Chaturvedi M, Köster D, Bossuyt PM, Gerke O, Jurke A, Kretzschmar ME, Lütgehetmann M, Mikolajczyk R, Reitsma JB, Schneiderhan-Marra N, Siebert U, Stekly C, Ehret C, Rübsamen N, Karch A, Zapf A.   +15 more
europepmc   +1 more source

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss, Judith A. Smith, Robert A. Colbert, Erin Treemarcki, Michael H. Weisman, Walter P. Maksymowych, Hermine I. Brunner, for the Childhood Arthritis and Rheumatology Research Alliance, Spondyloarthritis Research and Treatment Network, and Pediatric Rheumatology Collaborative Study Group Advisory Council   +9 more
wiley   +1 more source

The Central Role of the Global Emerging Infections Surveillance Program in Supporting Force Health Protection. [PDF]

Emerg Infect Dis
Early JM, Smith HJ, Cinkovich SS, Gallaway MS, Stager CN, Kasper MR.   +5 more
europepmc   +1 more source

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)

Arthritis Care &Research, EarlyView.
Objective Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS) syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures.
Kevin Byram, Heřman Mann, Danielle Hammond, Onima Chowdhury, Sinisa Savic, Yohei Kirino, Carmelo Gurnari, Maël Heiblig, Thibault Comont, Arsène Mekinian, Mrinal M. Patnaik, Lachelle D. Weeks, Gary Ho, Adam Al‐Hakim, Scott Goldberg, Marcela A. Ferrada, Sophie Georgin‐Lavialle, Peter C. Grayson, Emma M. Groarke, Bhavisha Patel, Megan Sullivan, Sarah A. Buckley, Bryan G. Harder, Raman Garcha, David B. Beck, Matthew J. Koster   +25 more
wiley   +1 more source

Trends in Incidence and Epidemiology of Methicillin-Resistant <i>Staphylococcus aureus</i> Bacteremia, Six Emerging Infections Program Surveillance Sites, 2005-2022. [PDF]

Open Forum Infect Dis
Biggs HM, Li R, Jackson KA, Nadle J, Petit S, Ray SM, Lynfield R, Como-Sabetti K, Dumyati G, Gellert A, Walsh M, Schaffner W, Baggs J, See I.   +13 more
europepmc   +1 more source

Individuals With Multijoint Osteoarthritis Demonstrate Larger Longitudinal Declines in Frailty: Data From the Canadian Longitudinal Study on Aging

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to test the hypothesis that multijoint osteoarthritis would modify the relation between time and frailty progression, in which more affected joints would lead to larger declines over six years compared to those without osteoarthritis using data from the Canadian Longitudinal Study on Aging.
Carson Halliwell, Rebecca Moyer, Myles W. O'Brien   +2 more
wiley   +1 more source

Optimizing the detection of emerging infections using mobility-based spatial sampling. [PDF]

Int J Appl Earth Obs Geoinf
Zhang D, Ge Y, Wang J, Liu H, Zhang WB, Wu X, B M Heuvelink G, Wu C, Yang J, Ruktanonchai NW, Qader SH, Ruktanonchai CW, Cleary E, Yao Y, Liu J, Nnanatu CC, Wesolowski A, Cummings DAT, Tatem AJ, Lai S.   +19 more
europepmc   +1 more source

Clinical Characteristics and Concordance of Anti‐MDA5 Antibodies: A Multicenter Australian Study

Arthritis Care &Research, EarlyView.
Objective In Australia, anti‐MDA5 antibodies are exclusively tested by a line immunoblot assay (LIA). The clinical concordance of an LIA‐positive anti‐MDA5 result is unclear. We aimed to describe the clinical features and determine the clinical concordance of patients with anti‐MDA5 antibodies. Methods Electronic records of a multisite cohort (patients
Syed B. Ali, Thomas Khoo, Keeran Shivakumar, Adam Caroll, Lauren Hender, Dimitra Beroukas, Kim Griggs, Celina Jin, Theo De Malmanche, Jessica Day, Gabor Major, Vidya Limaye   +11 more
wiley   +1 more source

The American Academy of Dermatology and International League of Dermatological Societies' Drug Resistant Dermatophytes (Tinea) Registry: The latest addition to the COVID-19, mpox, and Emerging Infections Registry. [PDF]

JAAD Int
Saunte DML, Khan S, Zehtab M, Caplan AS, Gold JAW, Smith DJ, Rosenbach M, Li C, Verma S, Castillo D, McMillen A, Elewski B, Lim HW, Desai SR, Hay R, Freeman EE.   +15 more
europepmc   +1 more source